Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: In Vivo Proarrhythmia Models of Drug-Induced Long QT Syndrome: Development of Chronic Atrioventricular Block Model of Microminipig.
A brand new in vivo proarrhythmia mannequin of drug-induced lengthy QT syndrome was developed utilizing the Microminipig, an extremely small minipig established by Fuji Micra Inc. (Shizuoka). The atrioventricular (AV) node of the Microminipig of both intercourse weighing roughly 6 - 7 kg was ablated underneath halothane anesthesia, and correct care was taken for them. Proarrhythmic results of medicine had been assessed at >2 months after the...