Systems Biology and Experimental Model Systems of Cancer

Systems Biology and Experimental Model Systems of Cancer

Over the previous decade, we’ve got witnessed an growing quantity of large-scale research which have supplied multi-omics information by high-throughput sequencing approaches. This has notably helped with figuring out key (epi)genetic alterations in cancers. Importantly, aberrations that result in the activation of signaling networks by way of the disruption of regular mobile homeostasis is seen …

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Experimental Biology 2020 Meeting Abstracts

Experimental Biology 2020 Meeting Abstracts

Bone morphogenetic proteins (BMPs) are progress components that belong to the remodeling progress factor-β (TGF-β) superfamily, and until date 15 BMPs have been described. BMPs, first described for his or her function in bone and cartilage formation, additionally play a task in renal fibrosis in persistent kidney illness (CKD). There is proof to point that …

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Training biochemistry students in experimental developmental biology: Induction of cardia bifida formation in the chick embryo

Training biochemistry students in experimental developmental biology: Induction of cardia bifida formation in the chick embryo

A excessive selection of experimental mannequin organisms have been used in developmental biology sensible lectures. The work with creating embryos is essential to make students conscious of the a number of organic phenomena underlying regular animal embryogenesis and morphogenesis and symbolize a novel experimental platform to research the affect of molecular signaling in the regulation …

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An overview of computational life science databases & exchange formats of relevance to chemical biology research.

An overview of computational life science databases & exchange formats of relevance to chemical biology research.

Databases and exchange formats describing organic entities reminiscent of chemical compounds and proteins, together with their relationships, are a essential element of analysis in life sciences disciplines, together with chemical biology whereby small details about small molecule properties converges with mobile and molecular biology. Databases for storing organic entities are rising not solely in dimension, …

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Research misconduct in health and life sciences research: A systematic review of retracted literature from Brazilian institutions.

Research misconduct in health and life sciences research: A systematic review of retracted literature from Brazilian institutions.

Measures to make sure analysis integrity have been extensively mentioned as a result of social, financial and scientific impression of analysis integrity. In the previous few years, monetary assist for health analysis in rising international locations has steadily elevated, ensuing in a rising quantity of scientific publications. These achievements, nonetheless, have been accompanied by an …

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Social support for collaboration and group awareness in life science research teams.

Social support for collaboration and group awareness in life science research teams.

Next-generation sequencing (NGS) applied sciences have revolutionarily reshaped the panorama of ‘-omics’ research areas. They produce a plethora of knowledge requiring particular data in pattern preparation, evaluation and characterization. Additionally, experience and competencies are required when utilizing bioinformatics instruments and strategies for environment friendly evaluation, interpretation, and visualization of knowledge. These abilities are hardly ever …

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"I am Primarily Paid for Publishing…": The Narrative Framing of Societal Responsibilities in Academic Life Science Research.

“I am Primarily Paid for Publishing…”: The Narrative Framing of Societal Responsibilities in Academic Life Science Research.

Building on group discussions and interviews with life science researchers in Austria, this paper analyses the narratives that researchers use in describing what they really feel accountable for, with a selected give attention to how they understand the societal tasks of their analysis. Our evaluation reveals that the core narratives utilized by the life scientists …

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Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: In Vivo Proarrhythmia Models of Drug-Induced Long QT Syndrome: Development of Chronic Atrioventricular Block Model of Microminipig.

Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: In Vivo Proarrhythmia Models of Drug-Induced Long QT Syndrome: Development of Chronic Atrioventricular Block Model of Microminipig.

A brand new in vivo proarrhythmia mannequin of drug-induced lengthy QT syndrome was developed utilizing the Microminipig, an extremely small minipig established by Fuji Micra Inc. (Shizuoka). The atrioventricular (AV) node of the Microminipig of both intercourse weighing roughly 6 – 7 kg was ablated underneath halothane anesthesia, and correct care was taken for them. …

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The Supervisory Role of Life Science Research Faculty: The Missing Link to Diversifying the Academic Workforce?

The Supervisory Role of Life Science Research Faculty: The Missing Link to Diversifying the Academic Workforce?

In addition to creating progressive analysis applications, life science analysis college at research-intensive establishments are tasked with offering profession mentoring and scientific coaching to new generations of scientists, together with postgraduate, graduate, and undergraduate college students. In this essay, we argue for a redefinition of mentoring in laboratory analysis, to totally distinguish three important roles …

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