Experimental Biology

Life Sience Research

Experimental Approaches for Examining Apicoplast Biology.

Experimental Approaches for Examining Apicoplast Biology.
Genetic manipulation is a robust instrument to check gene perform however figuring out the direct and first purposeful outcomes of any gene depletion is essential for this technique to be productive. This is a significant problem for the research of apicoplast biology, as a result of, within the absence of an environment friendly isolation methodology, apicoplast features have to be assayed within the parasite.
These assays must be carried out dynamically from the time of gene depletion, and embody requirements and controls that separate direct from oblique phenotypes. Here, we describe a pipeline for apicoplast purposeful evaluation and spotlight related mutant T. gondii cell traces and apicoplast markers which might be obtainable within the subject and that improve the specificity of phenotype description.

Dysfunctional RNA-binding protein biology and neurodegeneration in experimental autoimmune encephalomyelitis in feminine mice.

Altered stress granule (SG) and RNA-binding protein (RBP) biology have been proven to contribute to the pathogenesis of a number of neurodegenerative ailments, but little is thought about their position in a number of sclerosis (MS). Pathological options related to dysfunctional RBPs embody RBP mislocalization from its regular nuclear location to the cytoplasm and the formation of continual SGs.
We examined the speculation that altered SG and RBP biology may contribute to the neurodegeneration in experimental autoimmune encephalomyelitis (EAE). C57BL/6 feminine mice have been actively immunized with MOG35-55 to induce EAE. Spinal cords have been examined for mislocalization of the RBPs, heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) and TAR-DNA binding protein-43 (TDP-43), SGs, neurodegeneration (SMI-32), T cells (CD3), and macrophages (CD68).
In distinction to naive mice, mice with EAE confirmed SG formation (p < 0.0001) and mislocalization of hnRNP A1 (p < 0.05) in neurons of the ventral spinal wire grey matter, which correlated with scientific rating (R = 0.8104, p = 0.0253). In these identical areas, there was a neuronal loss (p < 0.0001) and elevated SMI-32 immunoreactivity (each markers of neurodegeneration) and elevated staining for CD3+ T cells and IFN-gamma. These findings recapitulate the SG and RBP biology and markers of neurodegeneration in MS tissues and recommend that altered SG and RBP biology contribute to the neurodegeneration in EAE, which could additionally apply to the pathogenesis of MS.

Advancing Global Change Biology Through Experimental Manipulations: Where Have We Been and Where Might We Go?

This commentary summarizes the publication historical past of Global Change Biology for works on experimental manipulations over the previous 25 years and highlights quite a few key publications. The retrospective abstract is then adopted by some ideas on the way forward for experimental work because it pertains to mechanistic understanding and methodological wants. Experiments for elevated CO2 atmospheres and anticipated warming eventualities which take us past historic analogs are recommended as future priorities.
Disturbance can be highlighted as a key agent of world change. Because experiments are demanding of each personnel effort and restricted fiscal sources, the allocation of experimental investments throughout Earth’s biomes must be performed in ecosystems of key significance. Uncertainty evaluation and broad neighborhood session must be used to establish analysis questions and goal biomes that may yield substantial good points in predictive confidence and societal relevance.
A full vary of methodological approaches protecting small to massive spatial scales will proceed to be justified as a supply of mechanistic understanding. Nevertheless, experiments working at bigger spatial scales encompassing organismal, edaphic, and environmental range of goal ecosystems are favored, as they permit for the evaluation of long run biogeochemical feedbacks enabling a full vary of inquiries to be addressed. Such research should additionally embody satisfactory funding in measurements of key interacting variables (e.g., water and nutrient availability and budgets) to allow mechanistic understanding of responses and to interpret context dependency.
Experimental Approaches for Examining Apicoplast Biology.
Integration of ecosystem-scale manipulations with centered process-based manipulations, networks, and large-scale observations will support extra full understanding of ecosystem responses, context dependence, and the extrapolation of outcomes. From the outset, these research have to be knowledgeable by and built-in with ecosystem fashions that present quantitative predictions from their embedded mechanistic hypotheses. A real two-way interplay between experiments and fashions will concurrently enhance the speed and robustness of Global Change analysis.

Implementation of the Chick Chorioallantoic Membrane (CAM) Model in Radiation Biology and Experimental Radiation Oncology Research.

Radiotherapy (RT) is a part of commonplace most cancers remedy. Innovations in remedy planning and elevated precision in dose supply have considerably improved the therapeutic achieve of radiotherapy however are reaching their limits as a consequence of biologic constraints. Thus, a greater understanding of the complicated native and systemic responses to RT and of the organic mechanisms inflicting remedy success or failure is required if we goal to outline novel targets for organic remedy optimization. Moreover, optimum remedy schedules and prognostic biomarkers need to be outlined for assigning sufferers to the perfect remedy possibility.
The complexity of the tumor atmosphere and of the radiation response requires in depth in vivo experiments for the validation of such therapies. So far in vivo investigations have principally been carried out in time- and cost-intensive murine fashions. Here we suggest the implementation of the chick chorioallantoic membrane (CAM) mannequin as a quick, cost-efficient mannequin for semi high-throughput preclinical in vivo screening of the modulation of the radiation results by molecularly focused medicine.

TIMP-2, Antibody

GWB-68C28E 7 ml Ask for price

anti- TIMP-1 antibody

FNab08706 100µg
EUR 658.5
Description: Antibody raised against TIMP-1

anti- Timp-3 antibody

FNab08708 100µg
EUR 658.5
Description: Antibody raised against Timp-3

anti- TIMP-4 antibody

FNab08709 100µg
EUR 658.5
Description: Antibody raised against TIMP-4

Anti-Human TIMP-1 Antibody

102-P252 100 µg
EUR 245.7
Description: TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.

Anti-Mouse TIMP-1 Antibody

103-M277 100 µg
EUR 399
Description: TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.

Anti-Human TIMP-1 Antibody

101-M123 100 µg
EUR 399
Description: TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.

Anti-Human TIMP-3 Antibody

101-M125 100 µg
EUR 399
Description: TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.

Anti-Human TIMP-4 Antibody

101-M126 100 µg
EUR 399
Description: TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.

TIMP Antibody

48342 100ul
EUR 429

TIMP-2 Polyclonal Antibody

41500 100ul
EUR 319

TIMP-2 Polyclonal Antibody

41500-100ul 100ul
EUR 302.4

TIMP-2 Polyclonal Antibody

41500-50ul 50ul
EUR 224.4

TIMP-2 Polyclonal Antibody

E041500 100μg/100μl
EUR 255
Description: Available in various conjugation types.

TIMP-2 Polyclonal Antibody

E20-74659 100ug
EUR 225
Description: Available in various conjugation types.

TIMP-2 Polyclonal Antibody

ABP52611-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of TIMP-2 from Human, Mouse, Rat. This TIMP-2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human TIMP-2 at AA range: 40-120

TIMP-2 Polyclonal Antibody

ABP52611-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of TIMP-2 from Human, Mouse, Rat. This TIMP-2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human TIMP-2 at AA range: 40-120

TIMP-2 Polyclonal Antibody

ABP52611-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of TIMP-2 from Human, Mouse, Rat. This TIMP-2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human TIMP-2 at AA range: 40-120

TIMP-2 Conjugated Antibody

C48343 100ul
EUR 476.4

TIMP-2 Polyclonal Antibody

E44H03653 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

TIMP-2 (Loop 6) Antibody

GWB-B0E29A 1 ml Ask for price

TIMP-2 (A47) polyclonal antibody

E43S1366 100ul
EUR 225
Description: Available in various conjugation types.

TIMP-1 Antibody

48342-100ul 100ul
EUR 399.6

TIMP-1 Antibody

48342-50ul 50ul
EUR 286.8

TIMP-4, Antibody

GWB-218B03 7 ml Ask for price

TIMP-3, Antibody

GWB-57E142 1 ml Ask for price

TIMP-1, Antibody

GWB-13BDAF 7 ml Ask for price

TIMP-3, Antibody

GWB-4F097C 0.1 mg Ask for price

TIMP-1 Antibody

GWB-1B64A4 0.1 mg Ask for price

TIMP-1 antibody

CAF50355-100ug 100ug
EUR 338

TIMP-1 Antibody

GWB-9B6903 0.1 mg Ask for price

TIMP-3, Antibody

GWB-7CDEA0 7 ml Ask for price

TIMP-1 Antibody

GWB-E078A8 0.1 mg Ask for price

TIMP-1 Antibody

GWB-Q00688 0.1 mg Ask for price

TIMP-4, Antibody

GWB-F5A57D 1 ml Ask for price

TIMP-1, Antibody

GWB-F78D2D 1 ml Ask for price

TIMP-2 Rabbit Polyclonal Antibody

ES3610-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against TIMP-2 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

TIMP-2 Rabbit Polyclonal Antibody

ES3610-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against TIMP-2 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Rabbit anti TIMP-4 Polyclonal Antibody

TA354938 100 µg Ask for price

Timp Metallopeptidase Inhibitor 2 (TIMP2) Antibody

20-abx116107
  • Ask for price
  • Ask for price
  • 150 ul
  • 50 ul

Polyclonal TIMP-3 Antibody

APR00530G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TIMP-3 . This antibody is tested and proven to work in the following applications:

Anti-Human TIMP-1 Rabbit Polyclonal Antibody

TA328449 100 µg Ask for price

TIMP-1 Human, Antibody

GWB-9E0FFB 0.1 mg Ask for price

TIMP Polyclonal Antibody

41499 100ul
EUR 319

Tissue Inhibitors of Metalloproteinase 2 (TIMP-2) Antibody

abx411650-1ml 1 ml
EUR 526.8

Tissue Inhibitors of Metalloproteinase 2 (TIMP-2) Antibody

abx238707-100ug 100 ug
EUR 610.8

TIMP-1 Polyclonal Antibody

41499-100ul 100ul
EUR 302.4

TIMP-1 Polyclonal Antibody

41499-50ul 50ul
EUR 224.4

TIMP-3 Polyclonal Antibody

41501 100ul
EUR 319

TIMP-3 Polyclonal Antibody

41501-100ul 100ul
EUR 302.4

TIMP-3 Polyclonal Antibody

41501-50ul 50ul
EUR 224.4

TIMP-4 Polyclonal Antibody

41502 100ul
EUR 319

TIMP-4 Polyclonal Antibody

41502-100ul 100ul
EUR 302.4

TIMP-4 Polyclonal Antibody

41502-50ul 50ul
EUR 224.4

TIMP-1 Polyclonal Antibody

E041499 100μg/100μl
EUR 255
Description: Available in various conjugation types.

TIMP-3 Polyclonal Antibody

E041501 100μg/100μl
EUR 255
Description: Available in various conjugation types.

TIMP-4 Polyclonal Antibody

E041502 100μg/100μl
EUR 255
Description: Available in various conjugation types.

TIMP-1 Polyclonal Antibody

E20-74658 100ug
EUR 225
Description: Available in various conjugation types.

TIMP-3 Polyclonal Antibody

E20-74660 100ug
EUR 225
Description: Available in various conjugation types.

TIMP-4 Polyclonal Antibody

E20-74661 100ug
EUR 225
Description: Available in various conjugation types.

TIMP-1 Polyclonal Antibody

ABP52610-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of TIMP-1 from Human, Mouse, Rat. This TIMP-1 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human TIMP-1 at AA range: 30-110

TIMP-1 Polyclonal Antibody

ABP52610-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of TIMP-1 from Human, Mouse, Rat. This TIMP-1 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human TIMP-1 at AA range: 30-110

TIMP-1 Polyclonal Antibody

ABP52610-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of TIMP-1 from Human, Mouse, Rat. This TIMP-1 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human TIMP-1 at AA range: 30-110

TIMP-3 Polyclonal Antibody

ABP52612-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of TIMP-3 from Human, Mouse, Rat. This TIMP-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human TIMP-3 at AA range: 60-140

TIMP-3 Polyclonal Antibody

ABP52612-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of TIMP-3 from Human, Mouse, Rat. This TIMP-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human TIMP-3 at AA range: 60-140

TIMP-3 Polyclonal Antibody

ABP52612-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of TIMP-3 from Human, Mouse, Rat. This TIMP-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human TIMP-3 at AA range: 60-140

TIMP-4 Polyclonal Antibody

ABP52613-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of TIMP-4 from Human, Mouse, Rat. This TIMP-4 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human TIMP-4 at AA range: 150-230

TIMP-4 Polyclonal Antibody

ABP52613-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of TIMP-4 from Human, Mouse, Rat. This TIMP-4 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human TIMP-4 at AA range: 150-230

TIMP-4 Polyclonal Antibody

ABP52613-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of TIMP-4 from Human, Mouse, Rat. This TIMP-4 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human TIMP-4 at AA range: 150-230

TIMP-1 Conjugated Antibody

C48342 100ul
EUR 476.4

TIMP-4 Polyclonal Antibody

ABP57524-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of TIMP-4 from Human. This TIMP-4 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from TIMP-4 at AA range: 174-223

TIMP-4 Polyclonal Antibody

ABP57524-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of TIMP-4 from Human. This TIMP-4 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from TIMP-4 at AA range: 174-223

TIMP-4 Polyclonal Antibody

ABP57524-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of TIMP-4 from Human. This TIMP-4 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from TIMP-4 at AA range: 174-223

TIMP-4 Polyclonal Antibody

E44H07241 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

TIMP-1 Polyclonal Antibody

E44H03652 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

TIMP-3 Polyclonal Antibody

E44H03654 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

TIMP-4 Polyclonal Antibody

E44H03655 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Human Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) Antibody

32733-05111 150 ug
EUR 215

Biotinylated Anti-Human TIMP-1 Rabbit Polyclonal Antibody

TA328448 50 µg Ask for price

Mouse Monoclonal anti-Human TIMP-2

hAP-0035 100ug
EUR 250

Mouse Monoclonal anti-Human TIMP-2

hAP-0035A 100ug
EUR 250

Human TIMP-1 Antibody Pair Set

ABPR-ZB241 5 plates, 15 plates Ask for price
Description: Quantitative determination of Human TIMP-1

TIMP-4 (S206) polyclonal antibody

E43S1477 100ul
EUR 225
Description: Available in various conjugation types.

TIMP-1 Rabbit Polyclonal Antibody

ES3609-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against TIMP-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

TIMP-1 Rabbit Polyclonal Antibody

ES3609-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against TIMP-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

TIMP-3 Rabbit Polyclonal Antibody

ES3611-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against TIMP-3 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

TIMP-3 Rabbit Polyclonal Antibody

ES3611-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against TIMP-3 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

TIMP-4 Rabbit Polyclonal Antibody

ES3612-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against TIMP-4 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

TIMP-4 Rabbit Polyclonal Antibody

ES3612-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against TIMP-4 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

TIMP-4 Rabbit Polyclonal Antibody

ES8517-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against TIMP-4 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

TIMP-4 Rabbit Polyclonal Antibody

ES8517-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against TIMP-4 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Anti-TIMP-2 antibody

PAab08707 100 ug
EUR 463.2

Anti-TIMP-2 antibody

STJ96024 200 µl
EUR 236.4
Description: Rabbit polyclonal to TIMP-2.

Anti-TIMP-2 antibody

STJ16100715 1 mL
EUR 856.8

Mouse Anti-Human TIMP-1 monoclonal antibody, clone NN14

CABT-ZB662 50 μl
EUR 595
Description: Mouse

Timp Metallopeptidase Inhibitor 1 (TIMP1) Antibody

20-abx116106
  • Ask for price
  • Ask for price
  • 150 ul
  • 50 ul

Timp Metallopeptidase Inhibitor 3 (TIMP3) Antibody

20-abx116108
  • Ask for price
  • Ask for price
  • 150 ul
  • 50 ul

Timp Metallopeptidase Inhibitor 4 (TIMP4) Antibody

20-abx116109
  • Ask for price
  • Ask for price
  • 150 ul
  • 50 ul

TIMP-3 Polyclonal Conjugated Antibody

C41501 100ul
EUR 476.4

TIMP-4 Polyclonal Conjugated Antibody

C41502 100ul
EUR 476.4

OASB01329-100UG - Human TIMP-4 Antibody

OASB01329-100UG 0.1mg
EUR 309

TIMP-2

E8RT1617 100ul
EUR 275
Description: Available in various conjugation types.

TIMP-2

MC-257 3A4 Ask for price

Human Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) Antibody (Biotin Conjugate)

32733-05121 150 ug
EUR 315

Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) Antibody

abx411648-01mg 0.1 mg
EUR 1312.8

Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) Antibody

abx411649-01mg 0.1 mg
EUR 1345.2

Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) Antibody

abx412170-01mg 0.1 mg
EUR 844.8

Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) Antibody

abx238706-100ug 100 ug
EUR 610.8

Tissue Inhibitors of Metalloproteinase 3 (Timp-3) Antibody

abx238708-100ug 100 ug
EUR 610.8

Tissue Inhibitors of Metalloproteinase 4 (TIMP-4) Antibody

abx238709-100ug 100 ug
EUR 610.8

Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) Antibody

abx023810-100ug 100 ug
EUR 978

Rat Monoclonal anti-mouse TIMP-1

mAP-0136 100ug
EUR 250

Mouse Monoclonal anti-Human TIMP-1

hAP-0034 100ug
EUR 250

Mouse Monoclonal anti-human TIMP-3

hAP-0036 100ug
EUR 250

Mouse Monoclonal anti-human TIMP-3

hAP-0036A 50ug
EUR 400

Mouse Monoclonal anti-Human TIMP-4

hAP-0037 100ug
EUR 250

Mouse Monoclonal anti-TIMP-2 Antibody

TA327966 100 µg Ask for price

Rat Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) Antibody

32520-05111 150 ug
EUR 215

Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) Antibody Pair

abx378053-96tests 96 tests
EUR 525

Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) Antibody Pair

abx378098-96tests 96 tests
EUR 525

Human Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) Antibody

32291-05111 150 ug
EUR 313.2

Mouse Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) Antibody

32293-05111 150 ug
EUR 215

Human Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) Antibody

32123-05111 150 ug
EUR 215

Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) Antibody (Biotin)

abx412171-50ug 50 ug
EUR 861.6

Anti-TIMP-1 antibody

PAab08706 100 ug
EUR 463.2

Anti-Timp-3 antibody

PAab08708 100 ug
EUR 463.2

Anti-TIMP-4 antibody

PAab08709 100 ug
EUR 463.2

Anti-TIMP-1 antibody

STJ96023 200 µl
EUR 236.4
Description: TIMP-1 is a protein encoded by the TIMP-1 gene which is approximately 23,2 kDa. TIMP-1 is involved in the GPCR pathway, phospholipase-C pathway, apoptotic pathways in synovial fibroblasts, ERK signalling and the CREB pathway. It functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signalling cascades via CD63 and ITGB1, it also acts as an inhibitor of MMPs which are groups of peptides involved in extracellular matrix degradation. TIMP-1 is secreted and is only active in the presence of disulphide bonds. It is ubiquitously expressed in numerous cells and tissues of the body. Mutations in the TIMP-1 gene may result in chronic venous leg ulcers and oral submucous fibrosis. STJ96023 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of TIMP-1 protein.

Anti-TIMP-3 antibody

STJ96025 200 µl
EUR 236.4
Description: Rabbit polyclonal to TIMP-3.

Anti-TIMP-4 antibody

STJ96026 200 µl
EUR 236.4
Description: Rabbit polyclonal to TIMP-4.

Anti-TIMP-4 antibody

STJ98630 200 µl
EUR 236.4
Description: Rabbit polyclonal to TIMP-4.

Anti-TIMP-1 antibody

STJ16100714 1 mL
EUR 856.8

Human Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) AssayLite™ Antibody (FITC Conjugate)

32733-05141 150 ug
EUR 370

Human Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) AssayLite™ Antibody (RPE Conjugate)

32733-05151 150 ug
EUR 370

Human Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) AssayLite™ Antibody (APC Cconjugate)

32733-05161 150 ug
EUR 370

Human Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) AssayLite™ Antibody (PerCP Conjugate)

32733-05171 150 ug
EUR 410

Human TIMP-4 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

EZ0524 5 plates/kit
EUR 370.8
Description: For the development of sandwich ELISA kit to measure human TIMP-4 in cell culture supernates, serum, plasma(heparin, EDTA) and human milk.

TIMP-2, human fibroblasts

7788-5 each
EUR 405.6

Recombinant Human TIMP-2

HEENP-2003 10ug Ask for price

Polyclonal TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) Antibody

APR00545G 7 ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) . This antibody is tested and proven to work in the following applications:

TIMP-2 Recombinant Protein

40-142-0002mg 0.002 mg
EUR 311.1
Description: TIMP-2 is an extracellular inhibitor of MMPs including MMP1, 2, 3, 7, 8, 9, 10, 12, 13, 14, 15, 16 and 19. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through an MMP-independent mechanism inhibiting endothelial cell proliferation in vitro and demonstrates anti-angiogenic activities in vivo. Recombinant human TIMP-2 is a 21.8 kDa protein containing 194 amino acid residues.

TIMP-2 Recombinant Protein

40-142-001mg 0.01 mg
EUR 437.1
Description: TIMP-2 is an extracellular inhibitor of MMPs including MMP1, 2, 3, 7, 8, 9, 10, 12, 13, 14, 15, 16 and 19. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through an MMP-independent mechanism inhibiting endothelial cell proliferation in vitro and demonstrates anti-angiogenic activities in vivo. Recombinant human TIMP-2 is a 21.8 kDa protein containing 194 amino acid residues.

TIMP-2 Recombinant Protein

91-415 0.05 mg
EUR 821.4
Description: Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

TIMP-2 Recombinant Protein

96-957 0.05 mg
EUR 619.8
Description: TIMP metallopeptidase inhibitor 2 is also known as TIMP2, which belongs to the protease inhibitor I35 (TIMP) family. This family protein are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The TIMP family encompasses four members (TIMP1, TIMP2, TIMP3, TIMP4), and they inhibit most MMPs by forming non-covalent binary complex. In addition to an inhibitory role against metalloproteinases, TIMP2 has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, TIMP-2 may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Rat Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) Antibody (Biotin Conjugate)

32520-05121 150 ug
EUR 315

Human Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) Antibody (Biotin Conjugate)

32291-05121 150 ug
EUR 442.8

Mouse Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) Antibody (Biotin Conjugate)

32293-05121 150 ug
EUR 315

Human Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) Antibody (Biotin Conjugate)

32123-05121 150 ug
EUR 315

Rat TIMP-2 ELISA Kit

ERT0523 96Tests
EUR 625.2

Rat TIMP-2 ELISA Kit

EK5587 96 tests
EUR 599

TIMP-2 (Rat) ELISA Kit

E4845-100 96 assays
EUR 697.2

Goat TIMP-2 ELISA Kit

EGTT0523 96Tests
EUR 625.2

Human TIMP-2 ELISA Kit

E16HE0100 96T
EUR 833.33

Mouse TIMP-2 ELISA Kit

EMT0523 96Tests
EUR 625.2

Sheep TIMP-2 ELISA Kit

EST0523 96Tests
EUR 625.2

TIMP-2 (Human) ELISA Kit

EKA51983-5x96T 5x96T Ask for price

TIMP-2 (Human) ELISA Kit

EKA51983-96T 96T
EUR 446.9

Human TIMP-2 ELISA Kit

EK5224 96 tests
EUR 599

Mouse TIMP-2 ELISA Kit

EK5434 96 tests
EUR 599

TIMP-2 ELISA KIT|Human

EF000232 96 Tests
EUR 826.8

TIMP-2 (Human) ELISA Kit

E4841-100 96 assays
EUR 697.2

Human TIMP-2 ELISA Kit

EHT0523 96Tests
EUR 625.2

Mouse TIMP-2 ELISA Kit

LF-EK50975 1×96T
EUR 777.6

TIMP-2 (Mouse) ELISA Kit

K4752-100 100 assays
EUR 970.8
Description: Sensitive, Colorimetric Assay

Human TIMP-2 ELISA Kit

RK00146 96T
EUR 280

Human TIMP-2 ELISA Kit

GWB-SKR167 96 Tests Ask for price

Human TIMP-2 ELISA Kit

GWB-ZZD116 1x96 well plate Ask for price

TIMP-3/ Rat TIMP- 3 ELISA Kit

ELA-E0129r 96 Tests
EUR 1063.2

TIMP-4/ Rat TIMP- 4 ELISA Kit

ELA-E0130r 96 Tests
EUR 1063.2

Monkey TIMP-2 ELISA Kit

EMKT0523 96Tests
EUR 625.2

Rabbit TIMP-2 ELISA Kit

ERTT0523 96Tests
EUR 625.2

Canine TIMP-2 ELISA Kit

ECT0523 96Tests
EUR 625.2

Bovine TIMP-2 ELISA Kit

EBT0523 96Tests
EUR 625.2

Porcine TIMP-2 ELISA Kit

EPT0523 96Tests
EUR 625.2

Chicken TIMP-2 ELISA Kit

ECKT0523 96Tests
EUR 625.2

TIMP-1

E8EM2001-03 100ul
EUR 275
Description: Available in various conjugation types.

TIMP-1

E8RT1616 100ul
EUR 275
Description: Available in various conjugation types.

TIMP-1

MC-255 102D1 Ask for price

Timp-3

PAB-606020058 0.1 mg
EUR 260

Anserini TIMP-2 ELISA Kit

EAT0523 96Tests
EUR 625.2

TIMP-2 (145-168) (human, bovine)

H-5998.0500 0.5mg
EUR 217.2
Description: Sum Formula: C131H189N33O35S3; CAS# [1872435-10-3] net

TIMP-2 (145-168) (human, bovine)

H-5998.1000 1.0mg
EUR 327.6
Description: Sum Formula: C131H189N33O35S3; CAS# [1872435-10-3] net

Human TIMP-2 Recombinant Protein

100-431 10 µg
EUR 196.35
Description: TIMP-2 is an extracellular inhibitor of MMPs including MMP1, 2, 3, 7, 8, 9, 10, 12, 13, 14, 15, 16 and 19. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through an MMP-independent mechanism inhibiting endothelial cell proliferation in vitro and demonstrates anti-angiogenic activities in vivo. Recombinant human TIMP-2 is a 21.8 kDa protein containing 194 amino acid residues.

Human TIMP-2 Recombinant Protein

100-431S 2 µg
EUR 92.4
Description: TIMP-2 is an extracellular inhibitor of MMPs including MMP1, 2, 3, 7, 8, 9, 10, 12, 13, 14, 15, 16 and 19. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through an MMP-independent mechanism inhibiting endothelial cell proliferation in vitro and demonstrates anti-angiogenic activities in vivo. Recombinant human TIMP-2 is a 21.8 kDa protein containing 194 amino acid residues.

Recombinant Human TIMP-2 Protein

PROTP16035-4 10ug
EUR 380.4
Description: TIMP-2 is an extracellular inhibitor of MMPs including MMP1, 2, 3, 7, 8, 9, 10, 12, 13, 14, 15, 16 and 19. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through an MMP-independent mechanism inhibiting endothelial cell proliferation in vitro and demonstrates anti-angiogenic activities in vivo. Recombinant human TIMP-2 is a 21.8 kDa protein containing 194 amino acid residues.

Polyclonal TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) Antibody - Without BSA

APR00535G 0.1mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) - Without BSA. This antibody is tested and proven to work in the following applications:

Polyclonal TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) Antibody - Without BSA

APR00541G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) - Without BSA. This antibody is tested and proven to work in the following applications:

Mouse Monoclonal anti-TIMP-1 Antibody

TA327965 100 µg Ask for price

Guinea Pig TIMP-2 ELISA Kit

EGT0523 96Tests
EUR 625.2

Nori Equine TIMP-2 ELISA Kit

GR106891 96-well
EUR 461

Human TIMP-2 Protein, His Tag

TI2-H5223 1mg
EUR 299.6
Description: Human TIMP-2, His Tag (TI2-H5223) is expressed from human 293 cells (HEK293). It contains AA Cys 27 - Pro 220 (Accession # NP_003246.1).

Rat TIMP-2 PicoKine ELISA Kit

EK1302 96 wells
EUR 510
Description: For quantitative detection of rat TIMP-2 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

TIMP-2 ELISA Kit (Rat) (OKBB00593)

OKBB00593 96 Wells
EUR 606
Description: Description of target: TIMP-2 gen is encoded by 5 exons spanning 83 kb of genomic DNA. TIMP-2 is 83 kilobase pairs (kb) long with exon-intron splicing sites located in preserved positions among the three members of the TIMP family. The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25. TIMP-2 abrogates angiogenic factor-induced endothelial cell proliferation in vitro and angiogenesis in vivo independent of MMP inhibition. The standard product used in this kit is recombinant human TIMP-2 with the molecular mass of 22Kda and 194 amino acid.;Species reactivity: Rat;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

Mouse TIMP-2 PicoKine ELISA Kit

EK0955 96 wells
EUR 510
Description: For quantitative detection of mouse TIMP-2 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

TIMP-2 ELISA Kit (Human) (OKBB00259)

OKBB00259 96 Tests
EUR 621.6
Description: Description of target: TIMP2 gen is encoded by 5 exons spanning 83 kb of genomic DNA. TIMP2 is 83 kilobase pairs (kb) long with exon-intron splicing sites located in preserved positions among the three members of the TIMP family. The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25. TIMP-2 abrogates angiogenic factor-induced endothelial cell proliferation in vitro and angiogenesis in vivo independent of MMP inhibition. The standard product used in this kit is recombinant human TIMP-2 with the molecular mass of 22Kda and 194 amino acid.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 2 pg/mL

TIMP-2 ELISA Kit (Mouse) (OKBB00476)

OKBB00476 96 Wells
EUR 606
Description: Description of target: TIMP-2 gen is encoded by 5 exons spanning 83 kb of genomic DNA. TIMP-2 is 83 kilobase pairs (kb) long with exon-intron splicing sites located in preserved positions among the three members of the TIMP family. The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25. TIMP-2 abrogates angiogenic factor-induced endothelial cell proliferation in vitro and angiogenesis in vivo independent of MMP inhibition. The standard product used in this kit is recombinant human TIMP-2 with the molecular mass of 22Kda and 194 amino acid.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

Human Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) AssayLite Antibody (FITC Conjugate)

32291-05141 150 ug
EUR 513.6

Human Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) AssayLite Antibody (RPE Conjugate)

32291-05151 150 ug
EUR 513.6

Human Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) AssayLite Antibody (APC Conjugate)

32291-05161 150 ug
EUR 513.6

Recombinant Human TIMP2/TIMP-2 Protein (Active)

PKSH031634-20ug 20ug
EUR 486
Description: Human

Human Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) AssayLite Antibody (PerCP Conjugate)

32291-05171 150 ug
EUR 565.2
This overview supplies a complete overview on the applying spectrum, benefits and limitations of the CAM assay and summarizes present information of its applicability for most cancers analysis with particular give attention to analysis in radiation biology and experimental radiation oncology.

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