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New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology.

Posted on by Marcus
New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology.
The American Society for Pharmacology and Experimental Therapeutics has revised the Instructions to Authors for Drug Metabolism and Disposition, Journal of Pharmacology and Experimental Therapeutics, and Molecular Pharmacology These revisions relate to knowledge evaluation (together with statistical evaluation) and reporting however don’t inform investigators the way to design and carry out their experiments.
Their general focus is on higher granularity in the outline of what has been carried out and discovered. Key suggestions embrace the necessity to differentiate between preplanned, hypothesis-testing, and exploratory experiments or research; explanations of whether or not key parts of research design, similar to pattern measurement and alternative of particular statistical assessments, had been specified earlier than any knowledge have been obtained or tailored thereafter; and explanations of whether or not any outliers (knowledge factors or total experiments) have been eradicated and when the foundations for doing so had been outlined.
Variability must be described by S.D. or interquartile vary, and precision must be described by confidence intervals; S.E. shouldn’t be used. P values must be used sparingly; in most circumstances, reporting variations or ratios (impact sizes) with their confidence intervals will likely be most well-liked. Depiction of information in figures ought to present as a lot granularity as doable, e.g., by changing bar graphs with scatter plots wherever possible and violin or box-and-whisker plots when not. This editorial explains the revisions and the underlying scientific rationale. We consider that these revised pointers will result in a much less biased and extra clear reporting of analysis findings.

New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology.

The American Society for Pharmacology and Experimental Therapeutics has revised the Instructions to Authors for Drug Metabolism and Disposition, Journal of Pharmacology and Experimental Therapeutics, and Molecular Pharmacology These revisions relate to knowledge evaluation (together with statistical evaluation) and reporting however don’t inform investigators the way to design and carry out their experiments.
Their general focus is on higher granularity in the outline of what has been carried out and discovered. Key suggestions embrace the necessity to differentiate between preplanned, hypothesis-testing, and exploratory experiments or research; explanations of whether or not key parts of research design, similar to pattern measurement and alternative of particular statistical assessments, had been specified earlier than any knowledge have been obtained or tailored thereafter; and explanations of whether or not any outliers (knowledge factors or total experiments) have been eradicated and when the foundations for doing so had been outlined.
Variability must be described by S.D. or interquartile vary, and precision must be described by confidence intervals; S.E. shouldn’t be used. P values must be used sparingly; in most circumstances, reporting variations or ratios (impact sizes) with their confidence intervals will likely be most well-liked. Depiction of information in figures ought to present as a lot granularity as doable, e.g., by changing bar graphs with scatter plots wherever possible and violin or box-and-whisker plots when not. This editorial explains the revisions and the underlying scientific rationale. We consider that these revised pointers will result in a much less biased and extra clear reporting of analysis findings.
New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology.

Extracting physiological data in experimental biology by way of Eulerian video magnification.

Videographic materials of animals can comprise inapparent indicators, similar to shade adjustments or movement that maintain details about physiological features, similar to coronary heart and respiration charge, pulse wave velocity, and vocalization. Eulerian video magnification permits the enhancement of such indicators to allow their detection.
The function of this research is to display how indicators related to experimental physiology will be extracted from non-contact videographic materials of animals.We utilized Eulerian video magnification to detect physiological indicators in a variety of experimental fashions and in captive and free ranging wildlife. Neotenic Mexican axolotls have been studied to display the extraction of coronary heart charge sign of non-embryonic animals from devoted videographic materials.
Heart charge might be acquired each in single and a number of animal setups of leucistic and usually coloured animals underneath totally different physiological situations (resting, exercised, or anesthetized) utilizing a variety of video qualities. Pulse wave velocity may be measured in the low blood strain system of the axolotl in addition to in the high-pressure system of the human being. Heart charge extraction was additionally doable from movies of acutely aware, unconstrained zebrafish and from non-dedicated videographic materials of sand lizard and giraffe.
This approach additionally allowed for coronary heart charge detection in embryonic chickens in ovo via the eggshell and in embryonic mice in utero and might be used as a gating sign to accumulate two-phase volumetric micro-CT knowledge of the beating embryonic hen coronary heart. Additionally, Eulerian video magnification was used to display how vocalization-induced vibrations will be detected in infrasound-producing Asian elephants.

Cyclin D1 Antibody
48497 100ul
EUR 429

Cyclin D1 Antibody
48497-100ul 100ul
EUR 399.6

Cyclin D1 Antibody
48497-50ul 50ul
EUR 286.8

Cyclin D1 Antibody
48619 100ul
EUR 529

Cyclin D1 Antibody
48619-100ul 100ul
EUR 399.6

Cyclin D1 Antibody
48619-50ul 50ul
EUR 286.8

Cyclin D1 Antibody
39315-100ul 100ul
EUR 468

Cyclin D1 Antibody
E18-0931-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Cyclin D1 Antibody
E18-0931-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Cyclin D1 Antibody
E18-6234-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Cyclin D1 Antibody
E18-6234-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Cyclin D1 Antibody
E80407-22 100ul 0.5mg/ml
EUR 225
Description: Available in various conjugation types.

Cyclin D1 Antibody
E80407-27 100μl
EUR 225
Description: Available in various conjugation types.

Cyclin D1 Antibody
DF6386 200ul
EUR 420

Cyclin D1 Antibody
DF6386-100ul 100ul
EUR 280

Cyclin D1 Antibody
DF6386-200ul 200ul
EUR 350

Cyclin D1 Antibody
E8RE6024 100ul
EUR 275
Description: Available in various conjugation types.

Cyclin D1 Antibody
E300456 100ug/200ul
EUR 275
Description: Available in various conjugation types.

Cyclin D1 Antibody
E301101 100ug/200ul
EUR 275
Description: Available in various conjugation types.

Cyclin D1 antibody
CAF50658-100ug 100ug
EUR 312

Cyclin D1 antibody
70R-13838 100 ug
EUR 484
Description: Affinity purified Mouse polyclonal Human Cyclin D1 antibody

Cyclin D1 antibody
70R-30875 100 ug
EUR 294
Description: Rabbit polyclonal Cyclin D1 antibody

Cyclin D1 antibody
70R-33524 100 ug
EUR 294
Description: Rabbit polyclonal Cyclin D1 antibody

Cyclin D1 Antibody
AF0931 200ul
EUR 420

Cyclin D1 Antibody
AF0931-100ul 100ul
EUR 280

Cyclin D1 Antibody
AF0931-200ul 200ul
EUR 350

Cyclin D1 Antibody
AF6234 200ul
EUR 420

Cyclin D1 Antibody
AF6234-100ul 100ul
EUR 280

Cyclin D1 Antibody
AF6234-200ul 200ul
EUR 350

Cyclin D1 Antibody
ABD6386 100ug
EUR 325

Cyclin D1 Antibody
ABF0931 100ug
EUR 325

Cyclin D1 Antibody
ABF6234 100ug
EUR 325

Cyclin D1 Antibody
GWB-36F9FE 0.1 ml Ask for price

Cyclin D1 Antibody
GWB-412C82 0.5 ml Ask for price

Cyclin D1 Antibody
GWB-182D3C 0.1 mg Ask for price

Cyclin D1 Antibody
GWB-1D3C35 0.1 ml Ask for price

Cyclin D1, Antibody
GWB-A57CFF 1 ml Ask for price

Cyclin D1 Antibody
GWB-AA2DFA 0.05 mg Ask for price

Cyclin D1 Antibody
GWB-6CFCAA 0.5 ml Ask for price

Cyclin D1 Antibody
GWB-7D2D45 0.01 mg Ask for price

Cyclin D1, Antibody
GWB-E16836 7 ml Ask for price

Cyclin D1, Antibody
GWB-E5624D 1 ml Ask for price

Cyclin D1, Antibody
GWB-CE0523 7 ml Ask for price

Cyclin D1, Antibody
GWB-DEA75D 0.1 ml Ask for price

Cyclin D1 Antibody
R20262-0.1ML 100ul
EUR 347.65
Description: This recombinant Cyclin D1 antibody reacts to human Cyclin D1. It may also react to the bovine, mouse or rat protein, as predicted by immunogen homology.

Cyclin D1 Antibody
R30348 100 ug
EUR 356.15
Description: D-type cyclins are regarded as essential links between cell environment and the core cell cycle machinery. Cyclin D1, the product of the human gene CCND1, is also known as BCL1. Cyclin D1 expression is regulated by the retinoblastoma protein. Expression of Cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. The CCND1 gene can function as an oncogene.

Cyclin D1 Antibody
R30349 100 ug
EUR 356.15
Description: Cyclin D1, also known as CCND1, belongs to the highly conserved cyclin family whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. CCND1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle. Amplification or overexpression of the protein plays pivotal roles in the development of a subset of human cancers including parathyroid adenoma, breast cancer, colon cancer, lymphoma, melanoma, and prostate cancer. The gene is overexpressed in breast cancers and is required for oncogene-induced tumorigenesis. Brisken et al. (2003) found that prolactin (PRL; 176760) induced IGF2 (147470) mRNA and IGF2 induced cyclin D1 protein expression in mouse mammary epithelial cultures. They also concluded that IGF2 is a mediator of prolactin-induced alveologenesis and that prolactin, IGF2, and Cyclin D1 are components of a developmental pathway in mammary gland.

Cyclin D1 Antibody
R36266-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: CCND1

Cyclin D1 Antibody
R32025 100 ug
EUR 356.15
Description: Cyclin D1, also known as CCND1, is a human gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle. Amplification or overexpression of cyclin D1 plays pivotal roles in the development of a subset of human cancers including parathyroid adenoma, breast cancer, colon cancer, lymphoma, melanoma, and prostate cancer. The cyclin D1 gene is overexpressed in human breast cancers and is required for oncogene-induced tumorigenesis. Brisken et al. (2003) found that prolactin induced IGF2 mRNA and IGF2 induced cyclin D1 protein expression in mouse mammary epithelial cultures. And they also concluded that IGF2 is a mediator of prolactin-induced alveologenesis and that prolactin, IGF2, and cyclin D1 are components of a developmental pathway in mammary gland.

Cyclin D1 Antibody
MBS9402668-01mL 0.1mL
EUR 420

Cyclin D1 Antibody
MBS9402668-5x01mL 5x0.1mL
EUR 1740

Cyclin D1 antibody
MBS8000589-01mg 0.1mg
EUR 515

Cyclin D1 antibody
MBS8000589-5x01mg 5x0.1mg
EUR 1780

Cyclin D1 Antibody
MBS857444-01mL 0.1mL
EUR 310

Cyclin D1 Antibody
MBS857444-01mLAF350 0.1mL(AF350)
EUR 570

Cyclin D1 Antibody
MBS857444-01mLAF405 0.1mL(AF405)
EUR 570

Cyclin D1 Antibody
MBS857444-01mLBiotin 0.1mL(Biotin)
EUR 570

Cyclin D1 Antibody
MBS857444-01mLFITC 0.1mL(FITC)
EUR 570

Cyclin D1 Antibody
MBS857385-01mL 0.1mL
EUR 320

Cyclin D1 Antibody
MBS8564641-01mL 0.1mL
EUR 305

Cyclin D1 Antibody
MBS8564641-01mLAF405L 0.1mL(AF405L)
EUR 565

Cyclin D1 Antibody
MBS8564641-01mLAF405S 0.1mL(AF405S)
EUR 565

Cyclin D1 Antibody
MBS8564641-01mLAF610 0.1mL(AF610)
EUR 565

Cyclin D1 Antibody
MBS8564641-01mLAF635 0.1mL(AF635)
EUR 565

Cyclin D1 Antibody
MBS8564645-01mL 0.1mL
EUR 305

Cyclin D1 Antibody
MBS8564645-01mLAF405L 0.1mL(AF405L)
EUR 565

Cyclin D1 Antibody
MBS8564645-01mLAF405S 0.1mL(AF405S)
EUR 565

Cyclin D1 Antibody
MBS8564645-01mLAF610 0.1mL(AF610)
EUR 565

Cyclin D1 Antibody
MBS8564645-01mLAF635 0.1mL(AF635)
EUR 565

Cyclin D1 Antibody
MBS854598-01mg 0.1mg
EUR 345

Cyclin D1 Antibody
MBS854598-01mLAF405L 0.1mL(AF405L)
EUR 565

Cyclin D1 Antibody
MBS854598-01mLAF405S 0.1mL(AF405S)
EUR 565

Cyclin D1 Antibody
MBS854598-01mLAF610 0.1mL(AF610)
EUR 565

Cyclin D1 Antibody
MBS854598-01mLAF635 0.1mL(AF635)
EUR 565

Cyclin D1 Antibody
MBS8512285-005mg 0.05mg
EUR 235

Cyclin D1 Antibody
MBS8512285-01mg 0.1mg
EUR 305

Cyclin D1 Antibody
MBS8512285-01mLAF405M 0.1mL(AF405M)
EUR 465

Cyclin D1 Antibody
MBS8512285-01mLAF546 0.1mL(AF546)
EUR 465

Cyclin D1 Antibody
MBS8512285-01mLAF750 0.1mL(AF750)
EUR 465

Cyclin D1 Antibody
MBS8511166-005mg 0.05mg
EUR 235

Cyclin D1 Antibody
MBS8511166-01mg 0.1mg
EUR 305

Cyclin D1 Antibody
MBS8511166-01mLAF405M 0.1mL(AF405M)
EUR 465

Cyclin D1 Antibody
MBS8511166-01mLAF546 0.1mL(AF546)
EUR 465

Cyclin D1 Antibody
MBS8511166-01mLAF750 0.1mL(AF750)
EUR 465

Cyclin D1 Antibody
MBS851751-01mg 0.1mg
EUR 345

Cyclin D1 Antibody
MBS851751-01mLAF405L 0.1mL(AF405L)
EUR 565

Cyclin D1 Antibody
MBS851751-01mLAF405S 0.1mL(AF405S)
EUR 565

Cyclin D1 Antibody
MBS851751-01mLAF610 0.1mL(AF610)
EUR 565

Cyclin D1 Antibody
MBS851751-01mLAF635 0.1mL(AF635)
EUR 565

Cyclin D1 antibody
MBS226537-01mL 0.1mL
EUR 485

Cyclin D1 antibody
MBS226537-5x01mL 5x0.1mL
EUR 2015

Cyclin D1 Antibody
MBS5312637-01mg 0.1mg
EUR 900

Cyclin D1 Antibody
MBS5312637-5x01mg 5x0.1mg
EUR 3905

Cyclin D1 antibody
MBS5309959-01mg 0.1mg
EUR 900

Cyclin D1 antibody
MBS5309959-5x01mg 5x0.1mg
EUR 3905

Cyclin D1 Antibody
MBS9434867-005mL 0.05mL
EUR 325

Cyclin D1 Antibody
MBS9434867-01mL 0.1mL
EUR 445

Cyclin D1 Antibody
MBS9434867-5x01mL 5x0.1mL
EUR 1860

Cyclin D1 Antibody
MBS9610353-01mL 0.1mL
EUR 260

Cyclin D1 Antibody
MBS9610353-02mL 0.2mL
EUR 305

Cyclin D1 Antibody
MBS9610353-5x02mL 5x0.2mL
EUR 1220

Cyclin D1 Antibody
MBS9435350-005mL 0.05mL
EUR 325

Cyclin D1 Antibody
MBS9435350-01mL 0.1mL
EUR 445

Cyclin D1 Antibody
MBS9435350-5x01mL 5x0.1mL
EUR 1860

Cyclin D1 Antibody
MBS9435470-005mL 0.05mL
EUR 315

Cyclin D1 Antibody
MBS9435470-01mL 0.1mL
EUR 455

Cyclin D1 Antibody
MBS9435470-5x01mL 5x0.1mL
EUR 1910

Cyclin D1 Antibody
MBS9607043-01mL 0.1mL
EUR 260

Cyclin D1 Antibody
MBS9607043-02mL 0.2mL
EUR 305

Cyclin D1 Antibody
MBS9607043-5x02mL 5x0.2mL
EUR 1220

Cyclin D1 Antibody
MBS9503530-005mL 0.05mL
EUR 285

Cyclin D1 Antibody
MBS9503530-01mL 0.1mL
EUR 385

Cyclin D1 Antibody
MBS9503530-5x01mL 5x0.1mL
EUR 1590

Cyclin D1 Antibody
MBS9503834-005mL 0.05mL
EUR 285

Cyclin D1 Antibody
MBS9503834-01mL 0.1mL
EUR 385

Cyclin D1 Antibody
MBS9503834-5x01mL 5x0.1mL
EUR 1590

Cyclin D1 Antibody
MBS9509357-005mL 0.05mL
EUR 285

Cyclin D1 Antibody
MBS9509357-01mL 0.1mL
EUR 385

Cyclin D1 Antibody
MBS9509357-5x01mL 5x0.1mL
EUR 1590

Cyclin D1 Antibody
MBS9600609-01mL 0.1mL
EUR 260

Cyclin D1 Antibody
MBS9600609-02mL 0.2mL
EUR 305

Cyclin D1 Antibody
MBS9600609-5x02mL 5x0.2mL
EUR 1220

Cyclin D1 Antibody
B0417-100ul 100μl
EUR 217
Description: Cyclin D1 Rabbit Polyclonal Antibody

Cyclin D1 Antibody
B0417-50ul 50μl
EUR 143.5
Description: Cyclin D1 Rabbit Polyclonal Antibody

Cyclin D1 Antibody
B0879-100ul 100μl
EUR 217
Description: Cyclin D1 Rabbit Polyclonal Antibody

Cyclin D1 Antibody
B0879-50ul 50μl
EUR 143.5
Description: Cyclin D1 Rabbit Polyclonal Antibody

anti- Cyclin D1 antibody
FNab02124 100µg
EUR 606.3
Description: Antibody raised against Cyclin D1

Anti- Cyclin D1 antibody
MBS177038-01mg 0.1mg
EUR 450

Anti- Cyclin D1 antibody
MBS177038-5x01mg 5x0.1mg
EUR 1870

Cyclin D1 antibody (HRP)
abx445238-100ug 100 ug
EUR 678

Cyclin D1 antibody: HRP
MBS8000602-01mg 0.1mg
EUR 555

Cyclin D1 antibody: HRP
MBS8000602-5x01mg 5x0.1mg
EUR 1965

Cyclin D1 antibody: RPE
MBS8000605-01mg 0.1mg
EUR 565

Cyclin D1 antibody: RPE
MBS8000605-5x01mg 5x0.1mg
EUR 2005

Cyclin D1 Antibody (S90)
MBS9214117-008mL 0.08mL
EUR 210

Cyclin D1 Antibody (S90)
MBS9214117-04mL 0.4mL
EUR 430

Cyclin D1 Antibody (S90)
MBS9214117-5x04mL 5x0.4mL
EUR 1910

Cyclin D1 antibody (FITC)
abx445237-100ug 100 ug
EUR 678

Cyclin D1 antibody: FITC
MBS8000601-01mg 0.1mg
EUR 560

Cyclin D1 antibody: FITC
MBS8000601-5x01mg 5x0.1mg
EUR 1985

Cyclin D1 Antibody (CCND1)
F47705-0.08ML 0.08 ml
EUR 140.25
Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.

Cyclin D1 Antibody (CCND1)
F48111-0.08ML 0.08 ml
EUR 140.25
Description: CCND1 is the regulatory component of the Cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. CyclinD-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. [UniProt]

Cyclin D1 Antibody (CCND1)
F48111-0.4ML 0.4 ml
EUR 322.15
Description: CCND1 is the regulatory component of the Cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. CyclinD-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. [UniProt]

Cyclin D1 Antibody (CCND1)
F49118-0.08ML 0.08 ml
EUR 140.25
Description: CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb.

Cyclin D1 Antibody (CCND1)
F40063-0.08ML 0.08 ml
EUR 140.25
Description: CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of the gene encoding this protein, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.

Cyclin D1 Antibody (CCND1)
F52187-0.08ML 0.08 ml
EUR 140.25
Description: Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin D1 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. Mutations, amplification and overexpression of the gene encoding this protein, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.

Cyclin D1 Antibody / CCND1
V8651-100UG 100 ug
EUR 349.3
Description: Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.

Cyclin D1 Antibody / CCND1
V8651-20UG 20 ug
EUR 153.3
Description: Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.

Cyclin D1 Antibody / CCND1
V8651SAF-100UG 100 ug
EUR 349.3
Description: Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.

Cyclin D1 Antibody / CCND1
V8652-100UG 100 ug
EUR 349.3
Description: Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Eulerian video magnification gives a method to extract inapparent temporal indicators from videographic materials of animals. This will be utilized in experimental and comparative physiology the place contact-based recordings (e.g., coronary heart charge) can’t be acquired.

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