A excessive selection of experimental mannequin organisms have been used in developmental biology sensible lectures. The work with creating embryos is essential to make students conscious of the a number of organic phenomena underlying regular animal embryogenesis and morphogenesis and symbolize a novel experimental platform to research the affect of molecular signaling in the regulation of all these processes.
In specific, Biochemistry undergraduate students take pleasure in each sensible and theoretical lectures on the molecular mechanisms of embryonic improvement, as that permits them for the integration of essential molecular ideas (e.g. signaling and sign transduction mechanisms; molecular patterning of improvement) into the dynamic and progressive context of animal embryonic ontogenesis.
Accordingly, you will need to rigorously design sensible laboratory lectures in developmental biology, as these are a novel pedagogical instruments fostering the pursuits of the students in this topic. This examine describes the design, implementation, and analysis of a two-session laboratory sensible exercise carried out by Biochemistry undergraduate students at University of Málaga (Spain).
In this sensible exercise, which takes benefit of the distinctive traits of the chick embryo, students find out how the vertebrate coronary heart types from the fusion of two bilateral-symmetric cardiac progenitor swimming pools below the steerage of the underlying endoderm. This low-cost and simple sensible laboratory exercise supplies related visible data on how experimental manipulations can severely affect anatomical type throughout organ improvement, in addition to a superb experimental setting to check molecular regulation of morphogenesis in an ex vivo (ex ovo) context.
Analysis of a COVID-19 Clinical Trial to Emphasize Experimental Design and Quantitative Reasoning in an Introductory Biology Course
Increasing scholar publicity to major literature in early biology coursework can improve scientific literacy and quantitative reasoning expertise. The efficacy of major literature dialogue is closely impacted by article choice, as scholar engagement is perfect with materials that’s topical and has clear relevance to actual world points. During the COVID-19 pandemic, the prevalence of COVID-19-related scientific analysis in the mainstream media makes it a great subject for present dialogue in entry-level biology programs.
Here, we current an exercise developed to facilitate a distant, synchronous dialogue of an open entry scientific trial publication on the experimental drug remdesivir in the remedy of COVID-19 (Beigel et al., 2020, N Engl J Med https://doi.org/10.1056/nejmoa2007764). The exercise, which is amenable to adaptation for different analysis articles, emphasizes ideas in experimental design, statistical evaluation, graphical interpretation, and the construction, content material, and group of typical sections of a major analysis article. Importantly, the exercise highlights the utility of the classroom response instrument Pear Deck, a Google Slides add-on, for creating participating literature discussions that may be readily tailored to all kinds of instructing modalities.
Experimental techniques biology approaches reveal interplay mechanisms in mannequin multispecies communities
Interactions between microorganisms in multispecies communities are thought to have substantial penalties for the neighborhood. Identifying the molecules and genetic pathways that contribute to such interaction is thus essential to know in addition to modulate neighborhood dynamics. Here I concentrate on latest research that make the most of experimental techniques biology strategies to check these phenomena in simplified mannequin microbial communities.
These unbiased biochemical and genomic approaches have recognized novel interactions and described the underlying genetic and molecular mechanisms. I talk about the insights offered by these research, describe progressive methods used to research much less tractable organisms and environments, and spotlight the utility of integrating these and extra focused strategies to comprehensively characterize interactions between species in microbial communities.
Experimental Methodologies to Visualize Early Cell Biology in Zebrafish Embryos
For organisms to perform usually, organic molecules should work at the appropriate time in the proper cells and inside the proper intracellular compartments of cells. Biological analysis depends closely on discovering the mobile areas at which such molecular interactions happen.
A mainstay method in this course of of discovery is the visualization of areas of proteins in cells and tissues, often called immunocytochemistry and immunohistochemistry, respectively. If carried out appropriately, these strategies can present detailed data concerning the endogenous areas of proteins and their ectopic areas or absence in mutants and in illness states.
Melanoma Single-Cell Biology in Experimental and Clinical Settings
Cellular heterogeneity is considered a significant factor for remedy response and resistance in a range of malignant tumors, together with malignant melanoma. More latest developments of single-cell sequencing know-how offered deeper insights into this phenomenon. Single-cell knowledge had been used to determine prognostic subtypes of melanoma tumors, with a particular emphasis on immune cells and fibroblasts in the tumor microenvironment.
Moreover, remedy resistance to checkpoint inhibitor remedy has been proven to be related to a set of differentially expressed immune cell signatures unraveling new targetable intracellular signaling pathways. Characterization of T cell states below checkpoint inhibitor remedy confirmed that exhausted CD8+ T cell sorts in melanoma lesions nonetheless have a excessive proliferative index.
Other research recognized remedy resistance mechanisms to focused remedy towards the mutated BRAF serine/threonine protein kinase together with repression of the melanoma differentiation gene microphthalmia-associated transcription issue (MITF) and induction of AXL receptor tyrosine kinase. Interestingly, remedy resistance mechanisms not solely included choice processes of pre-existing subclones but additionally transition between totally different states of gene expression.
ELISA kit for General Creatinine |
EK4382 |
SAB |
96 tests |
EUR 602.4 |
Description: Enzyme-linked immunosorbent assay kit for quantification of General Creatinine in samples from serum, plasma, tissue homogenates and other biological fluids. |
Creatinine ELISA Kit| Mouse Creatinine ELISA Kit |
EF013537 |
Lifescience Market |
96 Tests |
EUR 826.8 |
ELISA kit for Human Creatinine (Cr) |
KTE62273-48T |
Abbkine |
48T |
EUR 424.8 |
Description: Quantitative sandwich ELISA for measuring Human Creatinine (Cr) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Creatinine (Cr) |
KTE62273-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2702.4 |
Description: Quantitative sandwich ELISA for measuring Human Creatinine (Cr) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Creatinine (Cr) |
KTE62273-96T |
Abbkine |
96T |
EUR 686.4 |
Description: Quantitative sandwich ELISA for measuring Human Creatinine (Cr) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
Human Urinary Creatinine(Urinary Creatinine) ELISA Kit |
QY-E05390 |
Qayee Biotechnology |
96T |
EUR 433.2 |
Creatinine-HRP |
80-1133 |
Fitzgerald |
500 ul |
EUR 159.6 |
Description: Creatinine Conjugate for use in immunoassays |
ELISA kit for Human Urinary creatinine (UCR) |
KTE62727-48T |
Abbkine |
48T |
EUR 424.8 |
|
Description: Quantitative sandwich ELISA for measuring Human Urinary creatinine (UCR) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Urinary creatinine (UCR) |
KTE62727-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2702.4 |
|
Description: Quantitative sandwich ELISA for measuring Human Urinary creatinine (UCR) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Urinary creatinine (UCR) |
KTE62727-96T |
Abbkine |
96T |
EUR 686.4 |
|
Description: Quantitative sandwich ELISA for measuring Human Urinary creatinine (UCR) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
Creatinine N-HRP |
80-1132 |
Fitzgerald |
500 ul |
EUR 970.8 |
Description: Creatinine N Conjugate for use in immunoassays |
Creatinine Assay Kit |
abx098422-Hitachi7020R150ml3R250ml1 |
Abbexa |
Hitachi 7020; R1: 50ml×3 R2: 50ml×1 |
EUR 622.8 |
|
Creatinine Assay Kit |
abx098422-Hitachi7060R190ml2R260ml1 |
Abbexa |
Hitachi 7060; R1: 90ml×2 R2: 60ml×1 |
EUR 566.4 |
|
Creatinine Assay Kit |
abx098422-Toshiba120R140ml3R240ml1 |
Abbexa |
Toshiba 120; R1: 40ml×3 R2: 40ml×1 |
EUR 679.2 |
|
Creatinine Assay Kit |
abx098422-Toshiba120R150ml3R250ml1 |
Abbexa |
Toshiba 120; R1: 50ml×3 R2: 50ml×1 |
EUR 622.8 |
|
Creatinine Assay Kit |
abx098422-Toshiba40R150ml3R250ml1 |
Abbexa |
Toshiba 40; R1: 50ml×3 R2: 50ml×1 |
EUR 622.8 |
|
Creatinine Assay Kit |
55R-1467 |
Fitzgerald |
100 assays |
EUR 765.6 |
Description: Assay Kit for detection of Creatinine in the research laboratory |
Creatinine ELISA Kit |
DLR-Crtn-Ge-48T |
DL Develop |
48T |
EUR 562.8 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Creatinine in samples from serum, plasma, tissue homogenates or other biological fluids. |
Creatinine ELISA Kit |
DLR-Crtn-Ge-96T |
DL Develop |
96T |
EUR 729.6 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Creatinine in samples from serum, plasma, tissue homogenates or other biological fluids. |
Creatinine Assay Kit |
Z5030020 |
Biochain |
500 assays |
EUR 636 |
Creatinine N antibody |
20-1373 |
Fitzgerald |
100 ul |
EUR 1054.8 |
Description: Sheep polyclonal Creatinine N antibody |
Creatinine (Cr) CLIA Kit |
abx197924-96tests |
Abbexa |
96 tests |
EUR 990 |
|
Creatinine Acid antibody |
20-1244 |
Fitzgerald |
100 ul |
EUR 651.6 |
Description: Sheep polyclonal Creatinine Acid antibody |
Creatinine Standard, 100UL |
C003-100UL |
Arbor Assays |
100UL |
EUR 85 |
Creatinine Solution, 100ML |
X116-100ML |
Arbor Assays |
100ML |
EUR 94 |
Creatinine Solution, 25ML |
X120-25ML |
Arbor Assays |
25ML |
EUR 144 |
Creatinine (Cr) ELISA Kit |
abx257719-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
Creatinine (Cr) ELISA Kit |
abx350661-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
Rat Creatinine ELISA kit |
E02C0629-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rat Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Creatinine ELISA kit |
E02C0629-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rat Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Creatinine ELISA kit |
E02C0629-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rat Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Creatinine ELISA kit |
E08C0629-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Canine Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Creatinine ELISA kit |
E08C0629-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Canine Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Creatinine ELISA kit |
E08C0629-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Canine Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Creatinine ELISA kit |
E07C0629-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Creatinine ELISA kit |
E07C0629-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Creatinine ELISA kit |
E07C0629-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Creatinine (Rat) ELISA Kit |
E4370-100 |
Biovision |
each |
EUR 966 |
2‐AMINO ACETAMIDE HYDROCHLORIDE (GLYCINAMIDE HYDROCHLORIDE) |
101003 |
Survival Technologies |
each |
Ask for price |
Goat Creatinine ELISA kit |
E06C0629-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Goat Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Creatinine ELISA kit |
E06C0629-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Goat Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Creatinine ELISA kit |
E06C0629-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Goat Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Creatinine ELISA Kit |
DEIABL-M4 |
Creative Diagnostics |
96T |
EUR 752.4 |
Description: This CD Creatinine ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Mouse Creatinine. This ELISA kit for research use only, not for therapeutic or diagnostic applications! |
Human Creatinine ELISA kit |
E01C0629-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Human Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Creatinine ELISA kit |
E01C0629-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Human Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Creatinine ELISA kit |
E01C0629-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Human Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Creatinine ELISA kit |
E03C0629-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Creatinine ELISA kit |
E03C0629-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Creatinine ELISA kit |
E03C0629-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Creatinine (Human) ELISA Kit |
E4368-100 |
Biovision |
each |
EUR 907.2 |
Creatinine (Mouse) ELISA Kit |
E4369-100 |
Biovision |
each |
EUR 966 |
Rabbit Creatinine ELISA kit |
E04C0629-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Creatinine ELISA kit |
E04C0629-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Creatinine ELISA kit |
E04C0629-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Creatinine ELISA kit |
E09C0629-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Creatinine ELISA kit |
E09C0629-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Creatinine ELISA kit |
E09C0629-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Creatinine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Creatinine (Cr) CLIA Kit |
abx196865-96tests |
Abbexa |
96 tests |
EUR 990 |
|
DOI hydrochloride |
B5321-10 |
ApexBio |
10 mg |
EUR 205.2 |
DOI hydrochloride |
B5321-5 |
ApexBio |
5 mg |
EUR 141.6 |
DOI hydrochloride |
B5321-50 |
ApexBio |
50 mg |
EUR 714 |
DOB hydrochloride |
B5344-1 |
ApexBio |
1 mg |
EUR 141.6 |
Q94 hydrochloride |
B5705-10 |
ApexBio |
10 mg |
EUR 350.4 |
Q94 hydrochloride |
B5705-50 |
ApexBio |
50 mg |
EUR 1264.8 |
GMQ hydrochloride |
B5793-10 |
ApexBio |
10 mg |
EUR 212.4 |
GMQ hydrochloride |
B5793-50 |
ApexBio |
50 mg |
EUR 711.6 |
AMT hydrochloride |
B6480-10 |
ApexBio |
10 mg |
EUR 205.2 |
AMT hydrochloride |
B6480-100 |
ApexBio |
100 mg |
EUR 1036.8 |
AMT hydrochloride |
B6480-5 |
ApexBio |
5 mg |
EUR 141.6 |
AMT hydrochloride |
B6480-50 |
ApexBio |
50 mg |
EUR 673.2 |
General Creatinine ELISA Kit |
RDR-Crtn-Ge-48Tests |
Reddot Biotech |
48 Tests |
EUR 585.6 |
General Creatinine ELISA Kit |
RDR-Crtn-Ge-96Tests |
Reddot Biotech |
96 Tests |
EUR 811.2 |
General Creatinine ELISA Kit |
RD-Crtn-Ge-48Tests |
Reddot Biotech |
48 Tests |
EUR 560.4 |
General Creatinine ELISA Kit |
RD-Crtn-Ge-96Tests |
Reddot Biotech |
96 Tests |
EUR 775.2 |
Urinary Creatinine Assay Kit |
STA-378 |
Cell Biolabs |
192 assays |
EUR 518.4 |
Description: Cell Biolabs? Creatinine Assay Kit measures creatinine levels in urine. Samples are compared to a known concentration of creatinine standard within a 96-well microtiter plate format. Samples and standards are incubated for 30 minutes with a reaction reagent which changes color from yellow to bright orange upon reacting with creatinine, forming the creatinine-picrate complex. The plate is read with a standard 96-well spectrophotometric microplate reader at 490 nm. Higher OD values correlate with high creatinine concentrations. Sample creatinine concentrations are determined by comparison with the known creatinine standards. |
Urinary Creatinine Assay Kit |
UCR1 |
Detroit R&D |
1 Kit |
EUR 164.4 |
General Creatinine ELISA Kit |
RD-Crtn-Ge-48T |
Reddot Biotech |
48T |
EUR 401.3 |
|
Description: serum, plasma, tissue homogenates and other biological fluids. |
General Creatinine ELISA Kit |
RD-Crtn-Ge-96T |
Reddot Biotech |
96T |
EUR 573.3 |
|
Description: serum, plasma, tissue homogenates and other biological fluids. |
General Creatinine ELISA Kit |
RDR-Crtn-Ge-48T |
Reddot Biotech |
48T |
EUR 421.4 |
|
Description: serum, plasma, tissue homogenates and other biological fluids. |
General Creatinine ELISA Kit |
RDR-Crtn-Ge-96T |
Reddot Biotech |
96T |
EUR 602 |
|
Description: serum, plasma, tissue homogenates and other biological fluids. |
Rat Cr(Creatinine) ELISA Kit |
ER0864 |
FN Test |
96T |
EUR 628.92 |
|
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Rattus;Sensitivity: 0.75nmol/ml |
AMTB hydrochloride |
B2978-25 |
Biovision |
25 mg |
EUR 812.4 |
AMTB hydrochloride |
B2978-5 |
Biovision |
5 mg |
EUR 247.2 |
MPEP hydrochloride |
B1151-10 |
Biovision |
each |
EUR 222 |
MPEP hydrochloride |
B1151-50 |
Biovision |
each |
EUR 705.6 |
S1RA hydrochloride |
B1180-10 |
ApexBio |
10 mg |
EUR 1144.8 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
S1RA hydrochloride |
B1180-100 |
ApexBio |
100 mg |
EUR 4620 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
S1RA hydrochloride |
B1180-5 |
ApexBio |
5 mg |
EUR 819.6 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
S1RA hydrochloride |
B1180-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 895.2 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
S1RA hydrochloride |
B1180-50 |
ApexBio |
50 mg |
EUR 3316.8 |
Description: S1RA hydrochloride is a potent and selective antagonist of ?1 receptor (?1R) with Ki value of 17nM [1].S1RA is the first ?1 receptor antagonist with potent antinociceptive activities in various pain models. |
THZ1 Hydrochloride |
B4736-10 |
ApexBio |
10 mg |
EUR 268.8 |
Description: THZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1].THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an unanticipated means of achieving covalent selectivity. |
THZ1 Hydrochloride |
B4736-25 |
ApexBio |
25 mg |
EUR 477.6 |
Description: THZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1].THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an unanticipated means of achieving covalent selectivity. |
THZ1 Hydrochloride |
B4736-5 |
ApexBio |
5 mg |
EUR 170.4 |
Description: THZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1].THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an unanticipated means of achieving covalent selectivity. |
THZ1 Hydrochloride |
B4736-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 205.2 |
Description: THZ1 is a covalent inhibitor of CDK7 with IC50 value of 3.2nM [1].THZ1 covalently modifies CDK7 by targeting C312 residue outside of the kinase domain, providing an unanticipated means of achieving covalent selectivity. |
EHNA hydrochloride |
2265-25 |
Biovision |
each |
EUR 339.6 |
EHNA hydrochloride |
2265-5 |
Biovision |
each |
EUR 138 |
TAME Hydrochloride |
2050-100 |
Biovision |
each |
EUR 151.2 |
TAME Hydrochloride |
2050-1000 |
Biovision |
each |
EUR 574.8 |
TAME Hydrochloride |
2050-500 |
Biovision |
each |
EUR 405.6 |
DMCM hydrochloride |
B7268-10 |
ApexBio |
10 mg |
EUR 385.2 |
DMCM hydrochloride |
B7268-100 |
ApexBio |
100 mg |
EUR 2210.4 |
DMCM hydrochloride |
B7268-25 |
ApexBio |
25 mg |
EUR 776.4 |
DMCM hydrochloride |
B7268-5 |
ApexBio |
5 mg |
EUR 277.2 |
DMCM hydrochloride |
B7268-5.1 |
ApexBio |
10 mM (in 1mL H2O) |
EUR 297.6 |
DMCM hydrochloride |
B7268-50 |
ApexBio |
50 mg |
EUR 1363.2 |
TRIS hydrochloride |
B7299-500000 |
ApexBio |
500 g |
EUR 309.6 |
AMTB hydrochloride |
B7559-10 |
ApexBio |
10 mg |
EUR 459.6 |
AMTB hydrochloride |
B7559-50 |
ApexBio |
50 mg |
EUR 1746 |
MPEP Hydrochloride |
A3633-10 |
ApexBio |
10 mg |
EUR 142.8 |
Description: IC50: 36 nMMPEP is a potent, selective and systemically active mGlu5 receptor antagonist. Metabotropic glutamate (mGlu) receptors are a of G-protein-coupled receptor family linked to multiple second messengers and modulation of ion channel functions in the nervous system. |
MPEP Hydrochloride |
A3633-50 |
ApexBio |
50 mg |
EUR 379.2 |
Description: IC50: 36 nMMPEP is a potent, selective and systemically active mGlu5 receptor antagonist. Metabotropic glutamate (mGlu) receptors are a of G-protein-coupled receptor family linked to multiple second messengers and modulation of ion channel functions in the nervous system. |
MPTP hydrochloride |
A3634-10 |
ApexBio |
10 mg |
EUR 162 |
Description: IC50 Value: 53uM?inhibited the nerve-evoked twitches of phrenic nerve-hemidiaphragm preparations from ICR mice? . MPTP HCl (Sigma-Chem.) induced reduction in the DOPAC HVA/dopamine (DA) ratio and increase in striatal ascorbate (AS) oxidation in rats [1]. |
MPTP hydrochloride |
A3634-50 |
ApexBio |
50 mg |
EUR 344.4 |
Description: IC50 Value: 53uM?inhibited the nerve-evoked twitches of phrenic nerve-hemidiaphragm preparations from ICR mice? . MPTP HCl (Sigma-Chem.) induced reduction in the DOPAC HVA/dopamine (DA) ratio and increase in striatal ascorbate (AS) oxidation in rats [1]. |
MTEP hydrochloride |
A3636-10 |
ApexBio |
10 mg |
EUR 205.2 |
Description: IC50: 5 nMMTEP is a selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonist.The mGluRs are classified into three groups: group I (mGluR1 and 5), group II (mGluR2 and 3) and group III (mGluR4, 6, 7 and 8). |
MTEP hydrochloride |
A3636-5 |
ApexBio |
5 mg |
EUR 153.6 |
Description: IC50: 5 nMMTEP is a selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonist.The mGluRs are classified into three groups: group I (mGluR1 and 5), group II (mGluR2 and 3) and group III (mGluR4, 6, 7 and 8). |
MTEP hydrochloride |
A3636-50 |
ApexBio |
50 mg |
EUR 686.4 |
Description: IC50: 5 nMMTEP is a selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonist.The mGluRs are classified into three groups: group I (mGluR1 and 5), group II (mGluR2 and 3) and group III (mGluR4, 6, 7 and 8). |
PJ34 hydrochloride |
A4159-10 |
ApexBio |
10 mg |
EUR 142.8 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
A4159-5 |
ApexBio |
5 mg |
EUR 129.6 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
A4159-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 150 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
A4159-50 |
ApexBio |
50 mg |
EUR 296.4 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
PJ34 hydrochloride |
A4159-S |
ApexBio |
Evaluation Sample |
EUR 97.2 |
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM. |
TCEP hydrochloride |
B6055-10000 |
ApexBio |
10 g |
EUR 338.4 |
Description: Tris(2-carboxyethyl)phosphine hydrochloride (TCEP HCL) is a water soluble strong reducing agent that cleave disulfide bonds. It is a non-thiol and non-volatile solid. |
TCEP hydrochloride |
B6055-2000 |
ApexBio |
2 g |
EUR 150 |
Description: Tris(2-carboxyethyl)phosphine hydrochloride (TCEP HCL) is a water soluble strong reducing agent that cleave disulfide bonds. It is a non-thiol and non-volatile solid. |
TCEP hydrochloride |
B6055-50000 |
ApexBio |
50 g |
EUR 1243.2 |
Description: Tris(2-carboxyethyl)phosphine hydrochloride (TCEP HCL) is a water soluble strong reducing agent that cleave disulfide bonds. It is a non-thiol and non-volatile solid. |
HEAT hydrochloride |
B6339-10 |
ApexBio |
10 mg |
EUR 321.6 |
HEAT hydrochloride |
B6339-50 |
ApexBio |
50 mg |
EUR 1167.6 |
THIP hydrochloride |
B6460-100 |
ApexBio |
100 mg |
EUR 358.8 |
THIP hydrochloride |
B6460-25 |
ApexBio |
25 mg |
EUR 174 |
THIP hydrochloride |
B6460-50 |
ApexBio |
50 mg |
EUR 243.6 |
EHNA hydrochloride |
B6662-10 |
ApexBio |
10 mg |
EUR 145.2 |
EHNA hydrochloride |
B6662-25 |
ApexBio |
25 mg |
EUR 262.8 |
N20C hydrochloride |
B6980-10 |
ApexBio |
10 mg |
EUR 340.8 |
N20C hydrochloride |
B6980-50 |
ApexBio |
50 mg |
EUR 1245.6 |
TMPH hydrochloride |
B7053-10 |
ApexBio |
10 mg |
EUR 321.6 |
TMPH hydrochloride |
B7053-50 |
ApexBio |
50 mg |
EUR 1167.6 |
DAPI (hydrochloride) |
C3362-10 |
ApexBio |
10 mg |
EUR 146.4 |
DAPI (hydrochloride) |
C3362-25 |
ApexBio |
25 mg |
EUR 240 |
DAPI (hydrochloride) |
C3362-5 |
ApexBio |
5 mg |
EUR 111.6 |
AD57 (hydrochloride) |
C3080-1 |
ApexBio |
1 mg |
EUR 141.6 |
Description: IC50: 2 nM: blocks the receptor tyrosine kinase RET in Drosophila.AD57, as a polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer. |
AD57 (hydrochloride) |
C3080-10 |
ApexBio |
10 mg |
EUR 714 |
Description: IC50: 2 nM: blocks the receptor tyrosine kinase RET in Drosophila.AD57, as a polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer. |
AD57 (hydrochloride) |
C3080-5 |
ApexBio |
5 mg |
EUR 428.4 |
Description: IC50: 2 nM: blocks the receptor tyrosine kinase RET in Drosophila.AD57, as a polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer. |
THZ1 hydrochloride |
9544-25 |
Biovision |
each |
EUR 1227.6 |
THZ1 hydrochloride |
9544-5 |
Biovision |
each |
EUR 366 |
Taken collectively, single-cell know-how has offered deeper insights into melanoma biology and has put ahead our understanding of the position of tumor heterogeneity and transcriptional plasticity, which can affect on progressive scientific trial designs and experimental approaches.