Bone morphogenetic proteins (BMPs) are progress components that belong to the remodeling progress factor-β (TGF-β) superfamily, and until date 15 BMPs have been described. BMPs, first described for his or her function in bone and cartilage formation, additionally play a task in renal fibrosis in persistent kidney illness (CKD). There is proof to point that in rodent fashions of CKD, administration of recombinant BMP1-Three will increase renal fibrosis whereas administration of a BMP1-3-neutralizing antibody or BMP-7 antibody reduces renal fibrosis and preserves renal operate.
The purpose of the current research was to research modifications in gene expression within the renal cortex obtained from cats with kidney illness or calcium oxalate stone formers (CaOx) at necropsy, to establish BMPs related to renal dysfunction in cats and potential fibrosis. At time of demise the circulating ranges of creatinine in addition to symmetric dimethyl arginine (SDMA), each markers of kidney decline in cats, have been considerably greater in cats with renal illness (n=11) or stone-forming cats (CaOx, n=12) when in comparison with controls (n=19).
Using RNAseq in kidney tissue, we discovered a modest, however vital, improve within the expression of BMP-1 in cats with kidney illness (2.48 fold) and stone formers (1.72 fold), in comparison with controls (each p<0.01). While the rise in BMP-2 in CaOx cats was vital (1.46 fold; p<0.05 vs Con), the rise in cats with kidney illness was not (1.23 fold; NS). BMP2K, a BMP-2 inducible kinase, was considerably elevated in each kidney illness (1.43 fold) and CaOX (1.46 fold) (each p<0.05). In distinction, a big lower in BMP4 was noticed in each teams (<2.2 fold and 1.68 fold in kidney illness and CaOx, respectively; each p<0.001 vs Con).
A lower was additionally seen in CRIM 1, a protein related to podocyte filtration operate and whose discount is related to fibrosis, in each teams. BMP-7, whose potential therapeutic function in treating CKD and reversing fibrosis has been documented, was modestly decreased in each teams (each lower than 1.5 fold) in comparison with controls.
Given that there was a rise in all three types of TGFβ (TGFβ1, TGFβ2, and TGFβ3), a potent initiator of renal fibrosis, in each teams, and a decline in BMP-7, an endogenous inhibitor of TGFβ signaling in fibrosis, in comparison with controls, our outcomes profile the BMPs probably related to renal fibrosis in cats that will contribute to kidney dysfunction. In abstract, a dietary remedy to sluggish the development of kidney dysfunction might profit from the inclusion of dietary substances that attenuate renal fibrosis in cats. SUPPORT OR FUNDING INFORMATION: This research was funded by Hill’s Pet Nutrition, Inc.
Statins, bone biology and revision arthroplasty: evaluation of scientific and experimental proof
Osteoarthritis is a painful, disabling situation which is rising in prevalence on account of an ageing inhabitants. With no acknowledged disease-limiting therapeutics, arthroplasty of the hip and knee is the commonest and efficient remedy for decrease limb osteoarthritis, nonetheless decrease limb arthroplasty has a finite life-span and a proportion of sufferers would require revision arthroplasty.
With rising life expectancy and an rising proportion of youthful (<65 years) sufferers present process arthroplasty, the demand for revision arthroplasty after implant failure can be set to extend. Statins are cholesterol-modulating medication extensively used for cardiovascular threat discount which have been famous to have pleiotropic results together with probably influencing arthroplasty survival. In vitro research have demonstrated pleiotropic results in human bone cells, together with enhancement of osteoblastogenesis following simvastatin publicity, and in vivo research have demonstrated that intraperitoneal simvastatin can improve peri-implant bone progress in rats following titanium tibial implant insertion.
There is proof that statins can also affect osseointegration, enhancing bone progress on the bone-implant interface, subsequently enhancing the purposeful survival of implants. Data from the Danish Hip Arthroplasty Registry and the Clinical Practice Research Datalink within the UK recommend a discount within the threat of decrease limb revision arthroplasty in statin ever-users versus never-users, and a time-dependent impact of statins in lowering the danger of revision. In this text we evaluation the scientific and experimental proof linking statins and threat of revision arthroplasty.
Optimal Experimental Design for Systems and Synthetic Biology Using AMIGO2
Dynamic modeling in programs and artificial biology continues to be fairly a challenge-the complicated nature of the interactions leads to nonlinear fashions, which embody unknown parameters (or features). Ideally, time-series information assist the estimation of mannequin unknowns by means of information becoming. Goodness-of-fit measures would result in the very best mannequin amongst a set of candidates.
However, even when state-of-the-art measuring methods permit for an unprecedented quantity of information, not all information swimsuit dynamic modeling.Model-based optimum experimental design (OED) is meant to enhance mannequin predictive capabilities.
Recombinant Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS1395866-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 1055 |
Recombinant Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS1395866-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 1115 |
Recombinant Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS1395866-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1235 |
Recombinant Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS1395866-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1310 |
Recombinant Dog E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS956225-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1355 |
Recombinant Dog E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS956225-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 1050 |
Recombinant Dog E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS956225-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 1120 |
Recombinant Dog E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS956225-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1230 |
Recombinant Dog E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS956225-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1305 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS964250-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 320 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS964250-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 320 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS964250-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 520 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS964250-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 515 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS964250-05mgYeast | MyBiosource | 0.5mg(Yeast) | EUR 1260 |
Recombinant mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS9422390-002mg | MyBiosource | 0.02mg | EUR 380 |
Recombinant mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS9422390-01mg | MyBiosource | 0.1mg | EUR 650 |
Recombinant mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS9422390-05mg | MyBiosource | 0.5mg | EUR 1655 |
Recombinant mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS9422390-5x05mg | MyBiosource | 5x0.5mg | EUR 7290 |
Recombinant mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS9420451-002mg | MyBiosource | 0.02mg | EUR 380 |
Recombinant mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS9420451-01mg | MyBiosource | 0.1mg | EUR 650 |
Recombinant mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS9420451-1mg | MyBiosource | 1mg | EUR 2525 |
Recombinant mouse E3 ubiquitin-protein ligase Mdm2 |
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| MBS9420451-5x1mg | MyBiosource | 5x1mg | EUR 11205 |
Recombinant Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS951396-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1355 |
Recombinant Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS951396-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 1055 |
Recombinant Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS951396-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 1115 |
Recombinant Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS951396-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1235 |
Recombinant Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS951396-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1310 |
Mouse E3 ubiquitin-protein ligase Mdm2 (Mdm2) |
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| 1-CSB-EP013626MO | Cusabio |
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Description: Recombinant Mouse E3 ubiquitin-protein ligase Mdm2(Mdm2) expressed in E.coli |
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Mouse E3 ubiquitin-protein ligase Mdm2 (Mdm2) |
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| 1-CSB-YP013626MO | Cusabio |
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Description: Recombinant Mouse E3 ubiquitin-protein ligase Mdm2(Mdm2) expressed in Yeast |
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Recombinant Danio rerio E3 ubiquitin-protein ligase Mdm2 (mdm2) |
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| MBS1028911-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1315 |
Recombinant Danio rerio E3 ubiquitin-protein ligase Mdm2 (mdm2) |
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| MBS1028911-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 1000 |
Recombinant Danio rerio E3 ubiquitin-protein ligase Mdm2 (mdm2) |
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| MBS1028911-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 1105 |
Recombinant Danio rerio E3 ubiquitin-protein ligase Mdm2 (mdm2) |
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| MBS1028911-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1170 |
Recombinant Danio rerio E3 ubiquitin-protein ligase Mdm2 (mdm2) |
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| MBS1028911-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1260 |
Recombinant Xenopus laevis E3 ubiquitin-protein ligase Mdm2 (mdm2) |
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| MBS1120129-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1340 |
Recombinant Xenopus laevis E3 ubiquitin-protein ligase Mdm2 (mdm2) |
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| MBS1120129-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 1035 |
Recombinant Xenopus laevis E3 ubiquitin-protein ligase Mdm2 (mdm2) |
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| MBS1120129-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 1135 |
Recombinant Xenopus laevis E3 ubiquitin-protein ligase Mdm2 (mdm2) |
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| MBS1120129-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1210 |
Recombinant Xenopus laevis E3 ubiquitin-protein ligase Mdm2 (mdm2) |
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| MBS1120129-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1290 |
Recombinant Mesocricetus auratus E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS1280919-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1335 |
Recombinant Mesocricetus auratus E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS1280919-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 1025 |
Recombinant Mesocricetus auratus E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS1280919-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 1125 |
Recombinant Mesocricetus auratus E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS1280919-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1195 |
Recombinant Mesocricetus auratus E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| MBS1280919-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1285 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-1mg |
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| QP6353-ec-1mg | EnQuireBio | 1mg | EUR 2763.6 |
Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33932MO-48T | Abebio | 48T | EUR 325 |
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Description: Mouse (Mus musculus) |
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Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33932MO-48Tests | Abebio | 48 Tests | EUR 325 |
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Description: Mouse (Mus musculus) |
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Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33932MO-96T | Abebio | 96T | EUR 610 |
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Description: Mouse (Mus musculus) |
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Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33932MO-96Tests | Abebio | 96 Tests | EUR 610 |
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Description: Mouse (Mus musculus) |
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Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| EK9759 | SAB | 96Т | EUR 799 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-100ug |
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| QP6353-ec-100ug | EnQuireBio | 100ug | EUR 685.2 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-10ug |
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| QP6353-ec-10ug | EnQuireBio | 10ug | EUR 326.4 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-200ug |
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| QP6353-ec-200ug | EnQuireBio | 200ug | EUR 1077.6 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-500ug |
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| QP6353-ec-500ug | EnQuireBio | 500ug | EUR 1816.8 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-50ug |
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| QP6353-ec-50ug | EnQuireBio | 50ug | EUR 434.4 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-10ug |
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| QP6353-ye-10ug | EnQuireBio | 10ug | EUR 326.4 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-1mg |
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| QP6353-ye-1mg | EnQuireBio | 1mg | EUR 2763.6 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-50ug |
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| QP6353-ye-50ug | EnQuireBio | 50ug | EUR 424.8 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-100ug |
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| QP6353-ye-100ug | EnQuireBio | 100ug | EUR 685.2 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-200ug |
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| QP6353-ye-200ug | EnQuireBio | 200ug | EUR 1077.6 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-500ug |
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| QP6353-ye-500ug | EnQuireBio | 500ug | EUR 1806 |
Human E3 ubiquitin- protein ligase Mdm2, MDM2 ELISA KIT |
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| ELI-48185h | Lifescience Market | 96 Tests | EUR 988.8 |
Mouse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit |
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| MBS2890079-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 4080 |
Mouse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit |
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| MBS2890079-48StripWells | MyBiosource | 48-Strip-Wells | EUR 390 |
Mouse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit |
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| MBS2890079-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2220 |
Mouse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit |
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| MBS2890079-96StripWells | MyBiosource | 96-Strip-Wells | EUR 520 |
Recombinant human E3 ubiquitin-protein ligase Mdm2 |
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| P1360 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human E3 ubiquitin-protein ligase Mdm2 |
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ELISA kit for Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| KTE71081-48T | Abbkine | 48T | EUR 398.4 |
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Description: Quantitative sandwich ELISA for measuring Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| KTE71081-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2538 |
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Description: Quantitative sandwich ELISA for measuring Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| KTE71081-96T | Abbkine | 96T | EUR 646.8 |
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Description: Quantitative sandwich ELISA for measuring Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody |
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| abx344959-100l | Abbexa | 100 µl | EUR 350 |
E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody |
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| abx344959-50l | Abbexa | 50 µl | EUR 250 |
E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (HRP) |
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| abx344960-100g | Abbexa | 100 µg | Ask for price |
E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (HRP) |
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| abx344960-20g | Abbexa | 20 µg | EUR 250 |
E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (HRP) |
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| abx344960-50g | Abbexa | 50 µg | EUR 350 |
E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (FITC) |
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| abx344961-100g | Abbexa | 100 µg | Ask for price |
E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (FITC) |
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| abx344961-20g | Abbexa | 20 µg | EUR 250 |
E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (FITC) |
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| abx344961-50g | Abbexa | 50 µg | EUR 350 |
E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (Biotin) |
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| abx344962-100g | Abbexa | 100 µg | Ask for price |
E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (Biotin) |
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| abx344962-20g | Abbexa | 20 µg | EUR 250 |
E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (Biotin) |
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| abx344962-50g | Abbexa | 50 µg | EUR 350 |
Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33936CA-48T | Abebio | 48T | EUR 360 |
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Description: Cat (Felis catus,Feline) |
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Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33936CA-48Tests | Abebio | 48 Tests | EUR 360 |
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Description: Cat (Felis catus,Feline) |
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Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33936CA-96T | Abebio | 96T | EUR 680 |
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Description: Cat (Felis catus,Feline) |
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Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33936CA-96Tests | Abebio | 96 Tests | EUR 680 |
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Description: Cat (Felis catus,Feline) |
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Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| EK9763 | SAB | 96Т | EUR 799 |
Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| MBS285237-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6840 |
Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| MBS285237-48StripWells | MyBiosource | 48-Strip-Wells | EUR 480 |
Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| MBS285237-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3610 |
Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| MBS285237-96StripWells | MyBiosource | 96-Strip-Wells | EUR 805 |
Cat E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
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| MBS9335234-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Dog E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
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| MBS9331780-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Dog E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
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| MBS9331780-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Dog E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
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| MBS9331780-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Dog E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
|||
| MBS9331780-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33933HU-48T | Abebio | 48T | EUR 325 |
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Description: Human (Homo sapiens) |
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Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33933HU-48Tests | Abebio | 48 Tests | EUR 325 |
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Description: Human (Homo sapiens) |
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Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33933HU-96T | Abebio | 96T | EUR 610 |
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Description: Human (Homo sapiens) |
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Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33933HU-96Tests | Abebio | 96 Tests | EUR 610 |
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Description: Human (Homo sapiens) |
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Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33934HO-48T | Abebio | 48T | EUR 360 |
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Description: Horse (Equus caballus; Equine) |
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Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33934HO-48Tests | Abebio | 48 Tests | EUR 360 |
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Description: Horse (Equus caballus; Equine) |
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Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33934HO-96T | Abebio | 96T | EUR 680 |
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Description: Horse (Equus caballus; Equine) |
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Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
|||
| AE33934HO-96Tests | Abebio | 96 Tests | EUR 680 |
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Description: Horse (Equus caballus; Equine) |
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Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA KIT |
|||
| JOT-EK5213Hu | Jotbody | 96 wells | Ask for price |
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Description: Human |
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Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA KIT |
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| E5213Hu-1096T | Jiaxing Korain Biotech Ltd (BT Labs) | 10*96T | EUR 4122 |
Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA KIT |
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| E5213Hu-48wells | Jiaxing Korain Biotech Ltd (BT Labs) | 48 wells | EUR 300 |
Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA KIT |
|||
| E5213Hu-596T | Jiaxing Korain Biotech Ltd (BT Labs) | 5*96T | EUR 2061 |
Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA KIT |
|||
| E5213Hu-96wells | Jiaxing Korain Biotech Ltd (BT Labs) | 96 wells | EUR 458 |
Human E3 ubiquitin-protein ligase Mdm2(MDM2) Elisa Kit |
|||
| EK712991 | AFG Bioscience LLC | 96 Wells | EUR 0.31 |
Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
|||
| EK9760 | SAB | 96Т | EUR 799 |
Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
|||
| EK9761 | SAB | 96Т | EUR 799 |
Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
|||
| KTE61676-48T | Abbkine | 48T | EUR 339 |
|
Description: This Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit employs a two-site sandwich ELISA to quantitate MDM2. |
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Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
|||
| KTE61676-96T | Abbkine | 96T | EUR 589 |
|
Description: This Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit employs a two-site sandwich ELISA to quantitate MDM2. |
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Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
|||
| KTE61676-96T5 | Abbkine | 96 T×5 | EUR 2629 |
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Description: This Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit employs a two-site sandwich ELISA to quantitate MDM2. |
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Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
|||
| KTE61676-96T50 | Abbkine | 96 T×50 | EUR 24569 |
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Description: This Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit employs a two-site sandwich ELISA to quantitate MDM2. |
|||
Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
|||
| MBS1606129-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3460 |
Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
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| MBS1606129-48StripWells | MyBiosource | 48-Strip-Wells | EUR 285 |
Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
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| MBS1606129-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1750 |
Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
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| MBS1606129-96StripWells | MyBiosource | 96-Strip-Wells | EUR 425 |
Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| MBS280775-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6840 |
Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| MBS280775-48StripWells | MyBiosource | 48-Strip-Wells | EUR 480 |
Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| MBS280775-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3610 |
Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| MBS280775-96StripWells | MyBiosource | 96-Strip-Wells | EUR 805 |
Human E3 Ubiquitin-Protein Ligase Mdm2 (MDM2) ELISA Kit |
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| MBS9715340-48Tests | MyBiosource | 48Tests | EUR 340 |
Human E3 Ubiquitin-Protein Ligase Mdm2 (MDM2) ELISA Kit |
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| MBS9715340-5x96Tests | MyBiosource | 5x96Tests | EUR 1820 |
Human E3 Ubiquitin-Protein Ligase Mdm2 (MDM2) ELISA Kit |
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| MBS9715340-96Tests | MyBiosource | 96Tests | EUR 500 |
Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
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| MBS8807685-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3130 |
Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
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| MBS8807685-48StripWells | MyBiosource | 48-Strip-Wells | EUR 350 |
Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
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| MBS8807685-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1710 |
Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit |
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| MBS8807685-96StripWells | MyBiosource | 96-Strip-Wells | EUR 445 |
Dog MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit |
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| MBS2890075-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 4630 |
Dog MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit |
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| MBS2890075-48StripWells | MyBiosource | 48-Strip-Wells | EUR 440 |
Dog MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit |
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| MBS2890075-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2480 |
Dog MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit |
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| MBS2890075-96StripWells | MyBiosource | 96-Strip-Wells | EUR 580 |
MDM2, CK1d, Active, Recombinant, Human, GST-Tag (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) |
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| MBS636694-001mg | MyBiosource | 0.01mg | EUR 1310 |
MDM2, CK1d, Active, Recombinant, Human, GST-Tag (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) |
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| MBS636694-5x001mg | MyBiosource | 5x0.01mg | EUR 5685 |
Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33935DO-48T | Abebio | 48T | EUR 360 |
|
Description: Canine (Canis familiaris; Dog) |
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Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33935DO-48Tests | Abebio | 48 Tests | EUR 360 |
|
Description: Canine (Canis familiaris; Dog) |
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Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33935DO-96T | Abebio | 96T | EUR 680 |
|
Description: Canine (Canis familiaris; Dog) |
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Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| AE33935DO-96Tests | Abebio | 96 Tests | EUR 680 |
|
Description: Canine (Canis familiaris; Dog) |
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Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit |
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| EK9762 | SAB | 96Т | EUR 799 |
Mouse E3 ubiquitin-protein ligase Mdm2 ELISA kit |
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| E01A23588 | BlueGene | 96T | EUR 700 |
|
Description: ELISA |
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Mouse E3 ubiquitin-protein ligase Mdm2 ELISA kit |
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| E03M0702-48wellsplate | BlueGene | 48 wells plate | EUR 280 |
Mouse E3 ubiquitin-protein ligase Mdm2 ELISA kit |
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| E03M0702-96wellsplate | BlueGene | 96 wells plate | EUR 405 |
Horse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit |
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| MBS2890078-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 4080 |
Horse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit |
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| MBS2890078-48StripWells | MyBiosource | 48-Strip-Wells | EUR 390 |
Horse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit |
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| MBS2890078-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2220 |
Horse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit |
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| MBS2890078-96StripWells | MyBiosource | 96-Strip-Wells | EUR 520 |
Human MDM2 (E3 ubiquitin-protein ligase Mdm2) ELISA Kit |
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| MBS7615239-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3900 |
Human MDM2 (E3 ubiquitin-protein ligase Mdm2) ELISA Kit |
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| MBS7615239-48StripWells | MyBiosource | 48-Strip-Wells | EUR 340 |
Human MDM2 (E3 ubiquitin-protein ligase Mdm2) ELISA Kit |
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| MBS7615239-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2045 |
Human MDM2 (E3 ubiquitin-protein ligase Mdm2) ELISA Kit |
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| MBS7615239-96StripWells | MyBiosource | 96-Strip-Wells | EUR 455 |
Human E3 ubiquitin-Protein Ligase Mdm2, MDM2 GENLISA ELISA |
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| KBH5213 | Krishgen | 1 x 96 wells | EUR 286 |
MDM2 (untagged) - Human MDM2 proto-oncogene, E3 ubiquitin protein ligase (MDM2), transcript variant 5 |
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| SC335322 | Origene Technologies GmbH | 10 µg | Ask for price |
MDM2, Active, Recombinant, Human, c-Myc GST-Tag (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) |
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| MBS638318-001mg | MyBiosource | 0.01mg | EUR 1310 |
MDM2, Active, Recombinant, Human, c-Myc GST-Tag (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) |
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| MBS638318-5x001mg | MyBiosource | 5x0.01mg | EUR 5685 |
ELISA kit for Human E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| KTE61676-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Human E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (AP) |
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| MBS6132264-01mL | MyBiosource | 0.1(mL | EUR 875 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (AP) |
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| MBS6132264-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (PE) |
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| MBS6158779-01mL | MyBiosource | 0.1(mL | EUR 875 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (PE) |
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| MBS6158779-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
ELISA kit for Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| KTE20069-48T | Abbkine | 48T | EUR 424.8 |
|
Description: Quantitative sandwich ELISA for measuring Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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| KTE20069-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2702.4 |
|
Description: Quantitative sandwich ELISA for measuring Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
|||
ELISA kit for Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) |
|||
| KTE20069-96T | Abbkine | 96T | EUR 686.4 |
|
Description: Quantitative sandwich ELISA for measuring Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) APC |
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| MBS6137567-01mL | MyBiosource | 0.1(mL | EUR 875 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) APC |
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| MBS6137567-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (Biotin) |
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| MBS6142870-01mL | MyBiosource | 0.1(mL | EUR 875 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (Biotin) |
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| MBS6142870-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (FITC) |
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| MBS6148173-01mL | MyBiosource | 0.1(mL | EUR 875 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (FITC) |
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| MBS6148173-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (HRP) |
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| MBS6153476-01mL | MyBiosource | 0.1(mL | EUR 875 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (HRP) |
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| MBS6153476-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
ELISA Kit for Mouse E3 ubiquitin-protein ligase Mdm2 |
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| E12872m | EIAab | 96T | EUR 387.4 |
Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (AP) |
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| MBS6487469-02mL | MyBiosource | 0.2mL | EUR 980 |
Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (AP) |
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| MBS6487469-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (PE) |
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| MBS6487479-02mL | MyBiosource | 0.2mL | EUR 980 |
Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (PE) |
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| MBS6487479-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
MDM2 (myc-DDK-tagged) - Human MDM2 proto-oncogene, E3 ubiquitin protein ligase (MDM2), transcript variant 5 |
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| RC237428 | Origene Technologies GmbH | 10 µg | Ask for price |
MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (AP) |
|||
| MBS6487458-02mL | MyBiosource | 0.2mL | EUR 980 |
MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (AP) |
|||
| MBS6487458-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (APC) |
|||
| MBS6487459-02mL | MyBiosource | 0.2mL | EUR 980 |
MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (APC) |
|||
| MBS6487459-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (FITC) |
|||
| MBS6487461-02mL | MyBiosource | 0.2mL | EUR 980 |
MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (FITC) |
|||
| MBS6487461-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (PE) |
|||
| MBS6487468-02mL | MyBiosource | 0.2mL | EUR 980 |
MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (PE) |
|||
| MBS6487468-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (APC) |
|||
| MBS6487470-02mL | MyBiosource | 0.2mL | EUR 980 |
Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (APC) |
|||
| MBS6487470-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (Biotin) |
|||
| MBS6487471-02mL | MyBiosource | 0.2mL | EUR 980 |
Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (Biotin) |
|||
| MBS6487471-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (FITC) |
|||
| MBS6487472-02mL | MyBiosource | 0.2mL | EUR 980 |
Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (FITC) |
|||
| MBS6487472-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (MaxLight 550) |
|||
| MBS6212477-01mL | MyBiosource | 0.1(mL | EUR 875 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (MaxLight 550) |
|||
| MBS6212477-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (MaxLight 405) |
|||
| MBS6191127-01mL | MyBiosource | 0.1(mL | EUR 875 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (MaxLight 405) |
|||
| MBS6191127-5x01mL | MyBiosource | 5x0.1mL | EUR 3800 |
MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (Biotin) |
|||
| MBS6487460-02mL | MyBiosource | 0.2mL | EUR 980 |
MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (Biotin) |
|||
| MBS6487460-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (MaxLight 750) |
|||
| MBS6233827-01mL | MyBiosource | 0.1(mL | EUR 875 |
OED can be utilized to outline the set of experiments that might (a) establish the very best mannequin or (b) enhance the identifiability of unknown parameters. In this chapter, we current an in depth sensible process to compute optimum experiments utilizing the AMIGO2 toolbox.