Bone morphogenetic proteins (BMPs) are progress components that belong to the remodeling progress factor-β (TGF-β) superfamily, and until date 15 BMPs have been described. BMPs, first described for his or her function in bone and cartilage formation, additionally play a task in renal fibrosis in persistent kidney illness (CKD). There is proof to point that in rodent fashions of CKD, administration of recombinant BMP1-Three will increase renal fibrosis whereas administration of a BMP1-3-neutralizing antibody or BMP-7 antibody reduces renal fibrosis and preserves renal operate.
The purpose of the current research was to research modifications in gene expression within the renal cortex obtained from cats with kidney illness or calcium oxalate stone formers (CaOx) at necropsy, to establish BMPs related to renal dysfunction in cats and potential fibrosis. At time of demise the circulating ranges of creatinine in addition to symmetric dimethyl arginine (SDMA), each markers of kidney decline in cats, have been considerably greater in cats with renal illness (n=11) or stone-forming cats (CaOx, n=12) when in comparison with controls (n=19).
Using RNAseq in kidney tissue, we discovered a modest, however vital, improve within the expression of BMP-1 in cats with kidney illness (2.48 fold) and stone formers (1.72 fold), in comparison with controls (each p<0.01). While the rise in BMP-2 in CaOx cats was vital (1.46 fold; p<0.05 vs Con), the rise in cats with kidney illness was not (1.23 fold; NS). BMP2K, a BMP-2 inducible kinase, was considerably elevated in each kidney illness (1.43 fold) and CaOX (1.46 fold) (each p<0.05). In distinction, a big lower in BMP4 was noticed in each teams (<2.2 fold and 1.68 fold in kidney illness and CaOx, respectively; each p<0.001 vs Con).
A lower was additionally seen in CRIM 1, a protein related to podocyte filtration operate and whose discount is related to fibrosis, in each teams. BMP-7, whose potential therapeutic function in treating CKD and reversing fibrosis has been documented, was modestly decreased in each teams (each lower than 1.5 fold) in comparison with controls.
Given that there was a rise in all three types of TGFβ (TGFβ1, TGFβ2, and TGFβ3), a potent initiator of renal fibrosis, in each teams, and a decline in BMP-7, an endogenous inhibitor of TGFβ signaling in fibrosis, in comparison with controls, our outcomes profile the BMPs probably related to renal fibrosis in cats that will contribute to kidney dysfunction. In abstract, a dietary remedy to sluggish the development of kidney dysfunction might profit from the inclusion of dietary substances that attenuate renal fibrosis in cats. SUPPORT OR FUNDING INFORMATION: This research was funded by Hill’s Pet Nutrition, Inc.
Statins, bone biology and revision arthroplasty: evaluation of scientific and experimental proof
Osteoarthritis is a painful, disabling situation which is rising in prevalence on account of an ageing inhabitants. With no acknowledged disease-limiting therapeutics, arthroplasty of the hip and knee is the commonest and efficient remedy for decrease limb osteoarthritis, nonetheless decrease limb arthroplasty has a finite life-span and a proportion of sufferers would require revision arthroplasty.
With rising life expectancy and an rising proportion of youthful (<65 years) sufferers present process arthroplasty, the demand for revision arthroplasty after implant failure can be set to extend. Statins are cholesterol-modulating medication extensively used for cardiovascular threat discount which have been famous to have pleiotropic results together with probably influencing arthroplasty survival. In vitro research have demonstrated pleiotropic results in human bone cells, together with enhancement of osteoblastogenesis following simvastatin publicity, and in vivo research have demonstrated that intraperitoneal simvastatin can improve peri-implant bone progress in rats following titanium tibial implant insertion.

There is proof that statins can also affect osseointegration, enhancing bone progress on the bone-implant interface, subsequently enhancing the purposeful survival of implants. Data from the Danish Hip Arthroplasty Registry and the Clinical Practice Research Datalink within the UK recommend a discount within the threat of decrease limb revision arthroplasty in statin ever-users versus never-users, and a time-dependent impact of statins in lowering the danger of revision. In this text we evaluation the scientific and experimental proof linking statins and threat of revision arthroplasty.
Optimal Experimental Design for Systems and Synthetic Biology Using AMIGO2
Dynamic modeling in programs and artificial biology continues to be fairly a challenge-the complicated nature of the interactions leads to nonlinear fashions, which embody unknown parameters (or features). Ideally, time-series information assist the estimation of mannequin unknowns by means of information becoming. Goodness-of-fit measures would result in the very best mannequin amongst a set of candidates.
However, even when state-of-the-art measuring methods permit for an unprecedented quantity of information, not all information swimsuit dynamic modeling.Model-based optimum experimental design (OED) is meant to enhance mannequin predictive capabilities.
Mouse Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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DLR-MDM2-Mu-48T | DL Develop | 48T | EUR 632.4 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Mdm2 p53 Binding Protein Homolog (MDM2) in samples from tissue homogenates, cell lysates or other biological fluids. |
Mouse Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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DLR-MDM2-Mu-96T | DL Develop | 96T | EUR 825.6 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Mdm2 p53 Binding Protein Homolog (MDM2) in samples from tissue homogenates, cell lysates or other biological fluids. |
Mouse Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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RD-MDM2-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 639.6 |
Mouse Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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RD-MDM2-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 888 |
Mouse Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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RDR-MDM2-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 668.4 |
Mouse Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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RDR-MDM2-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 928.8 |
ELISA kit for Human E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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KTE61676-48T | Abbkine | 48T | EUR 398.4 |
Description: Quantitative sandwich ELISA for measuring Human E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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KTE61676-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2538 |
Description: Quantitative sandwich ELISA for measuring Human E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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KTE61676-96T | Abbkine | 96T | EUR 646.8 |
Description: Quantitative sandwich ELISA for measuring Human E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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KTE20069-48T | Abbkine | 48T | EUR 424.8 |
Description: Quantitative sandwich ELISA for measuring Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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KTE20069-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2702.4 |
Description: Quantitative sandwich ELISA for measuring Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) |
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KTE20069-96T | Abbkine | 96T | EUR 686.4 |
Description: Quantitative sandwich ELISA for measuring Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
Human Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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DLR-MDM2-Hu-48T | DL Develop | 48T | EUR 620.4 |
Description: A sandwich quantitative ELISA assay kit for detection of Human Mdm2 p53 Binding Protein Homolog (MDM2) in samples from tissue homogenates, cell lysates or other biological fluids. |
Human Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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DLR-MDM2-Hu-96T | DL Develop | 96T | EUR 807.6 |
Description: A sandwich quantitative ELISA assay kit for detection of Human Mdm2 p53 Binding Protein Homolog (MDM2) in samples from tissue homogenates, cell lysates or other biological fluids. |
Human Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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RD-MDM2-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 625.2 |
Human Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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RD-MDM2-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 867.6 |
Human Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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RDR-MDM2-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 652.8 |
Human Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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RDR-MDM2-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 907.2 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-100ug |
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QP6353-ye-100ug | EnQuireBio | 100ug | EUR 685.2 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-10ug |
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QP6353-ye-10ug | EnQuireBio | 10ug | EUR 326.4 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-1mg |
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QP6353-ye-1mg | EnQuireBio | 1mg | EUR 2763.6 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-200ug |
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QP6353-ye-200ug | EnQuireBio | 200ug | EUR 1077.6 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-500ug |
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QP6353-ye-500ug | EnQuireBio | 500ug | EUR 1806 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-50ug |
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QP6353-ye-50ug | EnQuireBio | 50ug | EUR 424.8 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-100ug |
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QP6353-ec-100ug | EnQuireBio | 100ug | EUR 685.2 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-10ug |
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QP6353-ec-10ug | EnQuireBio | 10ug | EUR 326.4 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-1mg |
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QP6353-ec-1mg | EnQuireBio | 1mg | EUR 2763.6 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-200ug |
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QP6353-ec-200ug | EnQuireBio | 200ug | EUR 1077.6 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-500ug |
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QP6353-ec-500ug | EnQuireBio | 500ug | EUR 1816.8 |
Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-50ug |
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QP6353-ec-50ug | EnQuireBio | 50ug | EUR 434.4 |
MDM2 Recombinant Protein (Mouse) |
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RP149951 | ABM | 100 ug | Ask for price |
Recombinant Mdm2 p53 Binding Protein Homolog (MDM2) |
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4-RPG790Hu01 | Cloud-Clone |
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Description: Recombinant Human Mdm2 p53 Binding Protein Homolog expressed in: E.coli |
Mouse Mdm2 p53 Binding Protein Homolog (MDM2) Protein |
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20-abx654330 | Abbexa |
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Mouse Mdm2 p53 Binding Protein Homolog (MDM2) Protein |
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20-abx654331 | Abbexa |
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MDM2 Recombinant Protein (Human) |
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RP070221 | ABM | 100 ug | Ask for price |
MDM2 Recombinant Protein (Rat) |
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RP211217 | ABM | 100 ug | Ask for price |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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20-abx173522 | Abbexa |
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Mdm2 P53 Binding Protein Homolog (MDM2) Antibody |
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20-abx133232 | Abbexa |
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Mdm2 P53 Binding Protein Homolog (MDM2) Antibody |
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20-abx134970 | Abbexa |
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Mdm2 P53 Binding Protein Homolog (MDM2) Antibody |
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20-abx128108 | Abbexa |
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Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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20-abx000690 | Abbexa |
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Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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20-abx013139 | Abbexa |
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Mdm2 P53 Binding Protein Homolog (MDM2) Antibody |
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20-abx008998 | Abbexa |
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Mdm2 P53 Binding Protein Homolog (MDM2) Antibody |
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abx038275-100ug | Abbexa | 100 ug | EUR 469.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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abx026874-400ul | Abbexa | 400 ul | EUR 627.6 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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abx026874-80l | Abbexa | 80 µl | EUR 343.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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abx026880-400ul | Abbexa | 400 ul | EUR 627.6 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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abx026880-80l | Abbexa | 80 µl | EUR 343.2 |
Mdm2 P53 Binding Protein Homolog (MDM2) Antibody |
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abx037448-100ug | Abbexa | 100 ug | EUR 469.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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abx332814-100ul | Abbexa | 100 ul | EUR 510 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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20-abx339679 | Abbexa |
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Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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abx330445-100ul | Abbexa | 100 ul | EUR 510 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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abx331992-100ul | Abbexa | 100 ul | EUR 510 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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abx449542-100ug | Abbexa | 100 ug | EUR 661.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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20-abx323164 | Abbexa |
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Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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20-abx323567 | Abbexa |
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Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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20-abx326184 | Abbexa |
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Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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20-abx326342 | Abbexa |
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Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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20-abx177517 | Abbexa |
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Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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20-abx177518 | Abbexa |
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Mdm2 p53 Binding Protein Homolog (MDM2) Antibody |
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abx235077-100ug | Abbexa | 100 ug | EUR 577.2 |
Active Mdm2 p53 Binding Protein Homolog (MDM2) |
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4-APG790Hu01 | Cloud-Clone |
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Description: Recombinant Human Mdm2 p53 Binding Protein Homolog expressed in: E.coli |
Mouse Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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20-abx154368 | Abbexa |
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Mouse Mdm2 p53 Binding Protein Homolog (MDM2) CLIA Kit |
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20-abx495297 | Abbexa |
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Mouse Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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SEG790Mu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 5834.88 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Mdm2 p53 Binding Protein Homolog (MDM2) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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SEG790Mu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 585.7 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Mdm2 p53 Binding Protein Homolog (MDM2) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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SEG790Mu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 785.28 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Mdm2 p53 Binding Protein Homolog (MDM2) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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SEG790Mu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3173.76 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Mdm2 p53 Binding Protein Homolog (MDM2) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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4-SEG790Mu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Mdm2 p53 Binding Protein Homolog (MDM2) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
Mouse Mdm2 p53 Binding Protein Homolog ELISA Kit (MDM2) |
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RK03022 | Abclonal | 96 Tests | EUR 625.2 |
Human Mdm2 p53 Binding Protein Homolog (MDM2) Protein |
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20-abx167861 | Abbexa |
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MDM2 Antibody |
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1-CSB-PA003212 | Cusabio |
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Description: A polyclonal antibody against MDM2. Recognizes MDM2 from Human, Mouse, Monkey. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/5000 |
MDM2 Antibody |
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1-CSB-PA11628A0Rb | Cusabio |
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Description: A polyclonal antibody against MDM2. Recognizes MDM2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500 |
MDM2 Antibody |
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1-CSB-PA005097 | Cusabio |
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Description: A polyclonal antibody against MDM2. Recognizes MDM2 from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000 |
MDM2 Antibody |
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1-CSB-PA010122 | Cusabio |
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Description: A polyclonal antibody against MDM2. Recognizes MDM2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/40000 |
MDM2 Antibody |
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1-CSB-PA010128 | Cusabio |
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Description: A polyclonal antibody against MDM2. Recognizes MDM2 from Human. This antibody is Unconjugated. Tested in the following application: IHC, IF, ELISA;IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/5000 |
MDM2 Antibody |
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1-CSB-PA973311 | Cusabio |
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Description: A polyclonal antibody against MDM2. Recognizes MDM2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:1000-1:2000, WB:1:200-1:1000 |
MDM2 Antibody |
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DF6100 | Affbiotech | 200ul | EUR 420 |
MDM2 Antibody |
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AF6376 | Affbiotech | 200ul | EUR 420 |
MDM2 Antibody |
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AF6964 | Affbiotech | 100ul | EUR 420 |
MDM2 Antibody |
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AF0208 | Affbiotech | 200ul | EUR 420 |
MDM2 Antibody |
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CSB-PA729984- | Cusabio | EUR 402 | |
Description: A polyclonal antibody against MDM2. Recognizes MDM2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000 |
MDM2 Antibody |
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CSB-PA729984-100ul | Cusabio | 100ul | EUR 379.2 |
Description: A polyclonal antibody against MDM2. Recognizes MDM2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000 |
MDM2 Antibody |
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CSB-PA891046- | Cusabio | EUR 402 | |
Description: A polyclonal antibody against MDM2. Recognizes MDM2 from Human, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
MDM2 Antibody |
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CSB-PA891046-100ul | Cusabio | 100ul | EUR 379.2 |
Description: A polyclonal antibody against MDM2. Recognizes MDM2 from Human, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
MDM2 antibody |
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70R-50052 | Fitzgerald | 100 ul | EUR 292.8 |
Description: Purified Polyclonal MDM2 antibody |
MDM2 antibody |
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70R-36433 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit polyclonal MDM2 antibody |
MDM2 antibody |
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70R-36777 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit Polyclonal MDM2 antibody |
MDM2 antibody |
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70R-51584 | Fitzgerald | 100 ul | EUR 344.4 |
Description: Purified Polyclonal MDM2 antibody |
MDM2 antibody |
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70R-31273 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit polyclonal MDM2 antibody |
MDM2 Antibody |
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48314-100ul | SAB | 100ul | EUR 399.6 |
MDM2 Antibody |
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48314-50ul | SAB | 50ul | EUR 286.8 |
MDM2 Antibody |
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32071-100ul | SAB | 100ul | EUR 302.4 |
MDM2 Peptide |
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45-878P | ProSci | 0.1 mg | EUR 405.6 |
Description: MDM2 Peptide |
MDM2 antibody |
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70R-13920 | Fitzgerald | 100 ug | EUR 386.4 |
Description: Affinity purified Rabbit polyclonal MDM2 antibody |
MDM2 antibody |
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20R-2687 | Fitzgerald | 50 ug | EUR 337.2 |
Description: Rabbit polyclonal MDM2 antibody |
MDM2 Antibody |
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21436-100ul | SAB | 100ul | EUR 302.4 |
MDM2 Antibody |
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21436-50ul | SAB | 50ul | EUR 224.4 |
MDM2 Antibody |
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35346-100ul | SAB | 100ul | EUR 468 |
MDM2 antibody |
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20R-2176 | Fitzgerald | 50 ug | EUR 337.2 |
Description: Rabbit polyclonal MDM2 antibody |
MDM2 antibody |
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20R-2506 | Fitzgerald | 50 ug | EUR 337.2 |
Description: Rabbit polyclonal MDM2 antibody |
MDM2 Antibody |
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33433-100ul | SAB | 100ul | EUR 302.4 |
MDM2 Antibody |
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33433-50ul | SAB | 50ul | EUR 224.4 |
MDM2 antibody |
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10-2548 | Fitzgerald | 250 ug | EUR 590.4 |
Description: Mouse monoclonal MDM2 antibody |
MDM2 Antibody |
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ABF0208 | Lifescience Market | 100 ug | EUR 525.6 |
MDM2 Antibody |
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ABF6376 | Lifescience Market | 100 ug | EUR 525.6 |
MDM2 Antibody |
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ABD6100 | Lifescience Market | 100 ug | EUR 525.6 |
MDM2 siRNA |
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20-abx923801 | Abbexa |
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MDM2 siRNA |
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20-abx923802 | Abbexa |
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anti-MDM2 |
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YF-PA24136 | Abfrontier | 50 ul | EUR 400.8 |
Description: Mouse polyclonal to MDM2 |
anti-MDM2 |
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YF-PA13097 | Abfrontier | 100 ul | EUR 483.6 |
Description: Rabbit polyclonal to MDM2 |
MDM2 Antibody |
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F42269-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
MDM2 Antibody |
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F42269-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
MDM2 Antibody |
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F42277-0.05ML | NSJ Bioreagents | 0.05 ml | EUR 165 |
MDM2 Antibody |
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F42277-0.2ML | NSJ Bioreagents | 0.2 ml | EUR 379 |
MDM2 Antibody |
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R30449 | NSJ Bioreagents | 100 ug | EUR 419 |
MDM2 Antibody |
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R33423-100UG | NSJ Bioreagents | 100 ug | EUR 399 |
MDM2 Antibody |
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RQ5828 | NSJ Bioreagents | 100 ug | EUR 419 |
MDM2 Antibody |
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V7305-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. |
MDM2 Antibody |
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V7305-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. |
MDM2 Antibody |
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V7305IHC-7ML | NSJ Bioreagents | 7 ml | EUR 499 |
Description: MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. |
MDM2 Antibody |
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V7305SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. |
MDM2 Antibody |
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V7950-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. |
MDM2 Antibody |
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V7950-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. |
MDM2 Antibody |
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V7950SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. |
MDM2 Antibody |
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V8985-100UG | NSJ Bioreagents | 100ug | EUR 499 |
Description: MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. |
MDM2 Antibody |
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V8985-20UG | NSJ Bioreagents | 20ug | EUR 219 |
Description: MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. |
MDM2 Antibody |
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V8985SAF-100UG | NSJ Bioreagents | 100ug | EUR 499 |
Description: MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. |
Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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abx595373-96tests | Abbexa | 96 tests | EUR 764.4 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (APC) |
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abx449552-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (Biotin) |
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abx449553-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (FITC) |
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abx449554-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (HRP) |
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abx449555-100ug | Abbexa | 100 ug | EUR 710.4 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (PerCP) |
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abx449557-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (RPE) |
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abx449558-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (Streptavidin) |
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abx449559-100ug | Abbexa | 100 ug | EUR 727.2 |
ELISA kit for Mouse MDM2 (Mdm2 p53 Binding Protein Homolog) |
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ELK6771 | ELK Biotech | 1 plate of 96 wells | EUR 518.4 |
Description: A sandwich ELISA kit for detection of Mdm2 p53 Binding Protein Homolog from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Siah E3 Ubiquitin Protein Ligase 1 (Recombinant) |
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20-abx073807 | Abbexa |
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Recombinant human E3 ubiquitin-protein ligase RNF152 |
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P1236 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase RNF152 |
Recombinant human E3 ubiquitin-protein ligase NEURL1B |
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P1306 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase NEURL1B |
Recombinant human E3 ubiquitin-protein ligase NEURL1 |
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P1308 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase NEURL1 |
Recombinant human E3 ubiquitin-protein ligase Arkadia |
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P1391 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase Arkadia |
Recombinant human E3 ubiquitin-protein ligase NEDD4 |
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P1638 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase NEDD4 |
Recombinant human E3 ubiquitin-protein ligase RNF146 |
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P1753 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase RNF146 |
Recombinant human E3 ubiquitin-protein ligase HECW1 |
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P1781 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase HECW1 |
Recombinant human E3 ubiquitin-protein ligase TRAIP |
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P1992 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase TRAIP |
Recombinant human E3 ubiquitin-protein ligase UBR3 |
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P2255 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase UBR3 |
Recombinant human E3 ubiquitin-protein ligase RNF220 |
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P2258 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase RNF220 |
Recombinant human E3 ubiquitin-protein ligase MSL2 |
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P2278 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase MSL2 |
Recombinant human E3 ubiquitin-protein ligase HECTD3 |
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P2326 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase HECTD3 |
Recombinant human E3 ubiquitin-protein ligase listerin |
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P2509 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase listerin |
Recombinant human E3 ubiquitin-protein ligase ZFP91 |
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P2644 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase ZFP91 |
Recombinant human E3 ubiquitin-protein ligase SHPRH |
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P2772 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase SHPRH |
Recombinant human E3 ubiquitin-protein ligase TRIM8 |
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P2834 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase TRIM8 |
Recombinant human E3 ubiquitin-protein ligase FANCL |
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P2841 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase FANCL |
Recombinant human E3 ubiquitin-protein ligase RNF43 |
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P2859 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase RNF43 |
Recombinant human E3 ubiquitin-protein ligase HACE1 |
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P2876 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human E3 ubiquitin-protein ligase HACE1 |
Mouse E3/ubiquitin-protein ligase(E3/UBPL)ELISA Kit |
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GA-E0992MS-48T | GenAsia Biotech | 48T | EUR 403.2 |
Mouse E3/ubiquitin-protein ligase(E3/UBPL)ELISA Kit |
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GA-E0992MS-96T | GenAsia Biotech | 96T | EUR 640.8 |
Mouse E3/ubiquitin-protein ligase(E3/UBPL)ELISA Kit |
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QY-E20505 | Qayee Biotechnology | 96T | EUR 433.2 |
Mouse E3 ubiquitin-protein ligase TRIM21 (Trim21) |
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1-CSB-EP733816MO | Cusabio |
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Description: Recombinant Mouse E3 ubiquitin-protein ligase TRIM21(Trim21) expressed in E.coli |
Mouse E3/ubiquitin protein ligase ELISA kit |
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E03E0118-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Mouse E3/ubiquitin protein ligase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse E3/ubiquitin protein ligase ELISA kit |
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E03E0118-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Mouse E3/ubiquitin protein ligase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse E3/ubiquitin protein ligase ELISA kit |
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E03E0118-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Mouse E3/ubiquitin protein ligase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Mdm2 p53 Binding Protein Homolog (MDM2) Protein (Active) |
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20-abx651414 | Abbexa |
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Mouse MDM2 shRNA Plasmid |
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20-abx971477 | Abbexa |
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E3 ubiquitin-protein ligase RAD18 Antibody |
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20-abx109280 | Abbexa |
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E3 ubiquitin-protein ligase TRIM11 Antibody |
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20-abx109281 | Abbexa |
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E3 ubiquitin-protein ligase MIB1 Antibody |
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20-abx109743 | Abbexa |
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anti-E3 ubiquitin-protein ligase MUL1 |
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YF-PA26608 | Abfrontier | 50 ul | EUR 400.8 |
Description: Mouse polyclonal to E3 ubiquitin-protein ligase MUL1 |
Human Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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20-abx152298 | Abbexa |
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Human Mdm2 p53 Binding Protein Homolog (MDM2) CLIA Kit |
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20-abx495296 | Abbexa |
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Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (ATTO 390) |
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abx449543-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (ATTO 488) |
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abx449544-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (ATTO 565) |
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abx449545-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (ATTO 594) |
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abx449546-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (ATTO 633) |
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abx449547-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (ATTO 655) |
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abx449548-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (ATTO 680) |
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abx449549-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (ATTO 700) |
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abx449550-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Antibody (Alkaline Phosphatase) |
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abx449551-100ug | Abbexa | 100 ug | EUR 727.2 |
Mdm2 p53 Binding Protein Homolog (MDM2) Polyclonal Antibody (Human) |
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4-PAG790Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Mdm2 p53 Binding Protein Homolog (MDM2) |
Human Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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SEG790Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 5677.8 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Mdm2 p53 Binding Protein Homolog (MDM2) in Tissue homogenates, cell lysates and other biological fluids. |
Human Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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SEG790Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 572.76 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Mdm2 p53 Binding Protein Homolog (MDM2) in Tissue homogenates, cell lysates and other biological fluids. |
Human Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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SEG790Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 766.8 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Mdm2 p53 Binding Protein Homolog (MDM2) in Tissue homogenates, cell lysates and other biological fluids. |
Human Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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SEG790Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3090.6 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Mdm2 p53 Binding Protein Homolog (MDM2) in Tissue homogenates, cell lysates and other biological fluids. |
Human Mdm2 p53 Binding Protein Homolog (MDM2) ELISA Kit |
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4-SEG790Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Mdm2 p53 Binding Protein Homolog (MDM2) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
Human Mdm2 p53 Binding Protein Homolog ELISA Kit (MDM2) |
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RK01831 | Abclonal | 96 Tests | EUR 625.2 |
Pomalidomide (E3 Ubiquitin Ligase Inhibitor) |
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SIH-581-25MG | Stressmarq | 25 mg | EUR 339.6 |
Description: The substance Pomalidomide is a e3 ubiquitin ligase inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is yellow powder which is May be dissolved in DMSO (50 mg/ml). |
Pomalidomide (E3 Ubiquitin Ligase Inhibitor) |
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SIH-581-5MG | Stressmarq | 5 mg | EUR 151.2 |
Description: The substance Pomalidomide is a e3 ubiquitin ligase inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is yellow powder which is May be dissolved in DMSO (50 mg/ml). |
MDM2 Polyclonal Antibody |
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ABP52917-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of MDM2 from Human. This MDM2 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human MDM2 |
MDM2 Polyclonal Antibody |
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ABP52917-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of MDM2 from Human. This MDM2 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human MDM2 |
MDM2 Polyclonal Antibody |
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ABP52917-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of MDM2 from Human. This MDM2 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human MDM2 |
MDM2 Blocking Peptide |
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DF6100-BP | Affbiotech | 1mg | EUR 234 |
MDM2 Blocking Peptide |
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AF6376-BP | Affbiotech | 1mg | EUR 234 |
MDM2 Blocking Peptide |
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AF0208-BP | Affbiotech | 1mg | EUR 234 |
MDM2 Conjugated Antibody |
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C48314 | SAB | 100ul | EUR 476.4 |
anti- MDM2 antibody |
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FNab05077 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against MDM2 |
MDM2 Polyclonal Antibody |
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ES2764-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against MDM2 from Human/Mouse/Monkey. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
OED can be utilized to outline the set of experiments that might (a) establish the very best mannequin or (b) enhance the identifiability of unknown parameters. In this chapter, we current an in depth sensible process to compute optimum experiments utilizing the AMIGO2 toolbox.