Experimental Biology

Life Sience Research

Experimental Biology 2020 Meeting Abstracts

Experimental Biology 2020 Meeting Abstracts
Bone morphogenetic proteins (BMPs) are progress components that belong to the remodeling progress factor-β (TGF-β) superfamily, and until date 15 BMPs have been described. BMPs, first described for his or her function in bone and cartilage formation, additionally play a task in renal fibrosis in persistent kidney illness (CKD). There is proof to point that in rodent fashions of CKD, administration of recombinant BMP1-Three will increase renal fibrosis whereas administration of a BMP1-3-neutralizing antibody or BMP-7 antibody reduces renal fibrosis and preserves renal operate.
The purpose of the current research was to research modifications in gene expression within the renal cortex obtained from cats with kidney illness or calcium oxalate stone formers (CaOx) at necropsy, to establish BMPs related to renal dysfunction in cats and potential fibrosis. At time of demise the circulating ranges of creatinine in addition to symmetric dimethyl arginine (SDMA), each markers of kidney decline in cats, have been considerably greater in cats with renal illness (n=11) or stone-forming cats (CaOx, n=12) when in comparison with controls (n=19).
Using RNAseq in kidney tissue, we discovered a modest, however vital, improve within the expression of BMP-1 in cats with kidney illness (2.48 fold) and stone formers (1.72 fold), in comparison with controls (each p<0.01). While the rise in BMP-2 in CaOx cats was vital (1.46 fold; p<0.05 vs Con), the rise in cats with kidney illness was not (1.23 fold; NS). BMP2K, a BMP-2 inducible kinase, was considerably elevated in each kidney illness (1.43 fold) and CaOX (1.46 fold) (each p<0.05). In distinction, a big lower in BMP4 was noticed in each teams (<2.2 fold and 1.68 fold in kidney illness and CaOx, respectively; each p<0.001 vs Con).
A lower was additionally seen in CRIM 1, a protein related to podocyte filtration operate and whose discount is related to fibrosis, in each teams. BMP-7, whose potential therapeutic function in treating CKD and reversing fibrosis has been documented, was modestly decreased in each teams (each lower than 1.5 fold) in comparison with controls.
Given that there was a rise in all three types of TGFβ (TGFβ1, TGFβ2, and TGFβ3), a potent initiator of renal fibrosis, in each teams, and a decline in BMP-7, an endogenous inhibitor of TGFβ signaling in fibrosis, in comparison with controls, our outcomes profile the BMPs probably related to renal fibrosis in cats that will contribute to kidney dysfunction. In abstract, a dietary remedy to sluggish the development of kidney dysfunction might profit from the inclusion of dietary substances that attenuate renal fibrosis in cats. SUPPORT OR FUNDING INFORMATION: This research was funded by Hill’s Pet Nutrition, Inc.

Statins, bone biology and revision arthroplasty: evaluation of scientific and experimental proof

Osteoarthritis is a painful, disabling situation which is rising in prevalence on account of an ageing inhabitants. With no acknowledged disease-limiting therapeutics, arthroplasty of the hip and knee is the commonest and efficient remedy for decrease limb osteoarthritis, nonetheless decrease limb arthroplasty has a finite life-span and a proportion of sufferers would require revision arthroplasty.
With rising life expectancy and an rising proportion of youthful (<65 years) sufferers present process arthroplasty, the demand for revision arthroplasty after implant failure can be set to extend. Statins are cholesterol-modulating medication extensively used for cardiovascular threat discount which have been famous to have pleiotropic results together with probably influencing arthroplasty survival. In vitro research have demonstrated pleiotropic results in human bone cells, together with enhancement of osteoblastogenesis following simvastatin publicity, and in vivo research have demonstrated that intraperitoneal simvastatin can improve peri-implant bone progress in rats following titanium tibial implant insertion.
 Experimental Biology 2020 Meeting Abstracts
There is proof that statins can also affect osseointegration, enhancing bone progress on the bone-implant interface, subsequently enhancing the purposeful survival of implants. Data from the Danish Hip Arthroplasty Registry and the Clinical Practice Research Datalink within the UK recommend a discount within the threat of decrease limb revision arthroplasty in statin ever-users versus never-users, and a time-dependent impact of statins in lowering the danger of revision. In this text we evaluation the scientific and experimental proof linking statins and threat of revision arthroplasty.

Optimal Experimental Design for Systems and Synthetic Biology Using AMIGO2

Dynamic modeling in programs and artificial biology continues to be fairly a challenge-the complicated nature of the interactions leads to nonlinear fashions, which embody unknown parameters (or features). Ideally, time-series information assist the estimation of mannequin unknowns by means of information becoming. Goodness-of-fit measures would result in the very best mannequin amongst a set of candidates.
However, even when state-of-the-art measuring methods permit for an unprecedented quantity of information, not all information swimsuit dynamic modeling.Model-based optimum experimental design (OED) is meant to enhance mannequin predictive capabilities.

Recombinant Cat E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS1395866-01mgEColi 0.1mg(E-Coli)
EUR 1235

Recombinant Cat E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS1395866-01mgYeast 0.1mg(Yeast)
EUR 1310

Recombinant Dog E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS956225-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1355

Recombinant Dog E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS956225-002mgEColi 0.02mg(E-Coli)
EUR 1050

Recombinant Dog E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS956225-002mgYeast 0.02mg(Yeast)
EUR 1120

Recombinant Dog E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS956225-01mgEColi 0.1mg(E-Coli)
EUR 1230

Recombinant Dog E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS956225-01mgYeast 0.1mg(Yeast)
EUR 1305

Recombinant mouse E3 ubiquitin-protein ligase Mdm2

MBS9422390-002mg 0.02mg
EUR 380

Recombinant mouse E3 ubiquitin-protein ligase Mdm2

MBS9422390-01mg 0.1mg
EUR 650

Recombinant mouse E3 ubiquitin-protein ligase Mdm2

MBS9422390-05mg 0.5mg
EUR 1655

Recombinant mouse E3 ubiquitin-protein ligase Mdm2

MBS9422390-5x05mg 5x0.5mg
EUR 7290

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2

MBS964250-002mgEColi 0.02mg(E-Coli)
EUR 320

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2

MBS964250-002mgYeast 0.02mg(Yeast)
EUR 320

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2

MBS964250-01mgEColi 0.1mg(E-Coli)
EUR 520

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2

MBS964250-01mgYeast 0.1mg(Yeast)
EUR 515

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2

MBS964250-05mgYeast 0.5mg(Yeast)
EUR 1260

Recombinant mouse E3 ubiquitin-protein ligase Mdm2

MBS9420451-002mg 0.02mg
EUR 380

Recombinant mouse E3 ubiquitin-protein ligase Mdm2

MBS9420451-01mg 0.1mg
EUR 650

Recombinant mouse E3 ubiquitin-protein ligase Mdm2

MBS9420451-1mg 1mg
EUR 2525

Recombinant mouse E3 ubiquitin-protein ligase Mdm2

MBS9420451-5x1mg 5x1mg
EUR 11205

Recombinant Horse E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS951396-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1355

Recombinant Horse E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS951396-002mgEColi 0.02mg(E-Coli)
EUR 1055

Recombinant Horse E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS951396-002mgYeast 0.02mg(Yeast)
EUR 1115

Recombinant Horse E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS951396-01mgEColi 0.1mg(E-Coli)
EUR 1235

Recombinant Horse E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS951396-01mgYeast 0.1mg(Yeast)
EUR 1310

Mouse E3 ubiquitin-protein ligase Mdm2 (Mdm2)

1-CSB-YP013626MO
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Description: Recombinant Mouse E3 ubiquitin-protein ligase Mdm2(Mdm2) expressed in Yeast

Mouse E3 ubiquitin-protein ligase Mdm2 (Mdm2)

1-CSB-EP013626MO
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Description: Recombinant Mouse E3 ubiquitin-protein ligase Mdm2(Mdm2) expressed in E.coli

Recombinant Danio rerio E3 ubiquitin-protein ligase Mdm2 (mdm2)

MBS1028911-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1315

Recombinant Danio rerio E3 ubiquitin-protein ligase Mdm2 (mdm2)

MBS1028911-002mgEColi 0.02mg(E-Coli)
EUR 1000

Recombinant Danio rerio E3 ubiquitin-protein ligase Mdm2 (mdm2)

MBS1028911-002mgYeast 0.02mg(Yeast)
EUR 1105

Recombinant Danio rerio E3 ubiquitin-protein ligase Mdm2 (mdm2)

MBS1028911-01mgEColi 0.1mg(E-Coli)
EUR 1170

Recombinant Danio rerio E3 ubiquitin-protein ligase Mdm2 (mdm2)

MBS1028911-01mgYeast 0.1mg(Yeast)
EUR 1260

Recombinant Xenopus laevis E3 ubiquitin-protein ligase Mdm2 (mdm2)

MBS1120129-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1340

Recombinant Xenopus laevis E3 ubiquitin-protein ligase Mdm2 (mdm2)

MBS1120129-002mgEColi 0.02mg(E-Coli)
EUR 1035

Recombinant Xenopus laevis E3 ubiquitin-protein ligase Mdm2 (mdm2)

MBS1120129-002mgYeast 0.02mg(Yeast)
EUR 1135

Recombinant Xenopus laevis E3 ubiquitin-protein ligase Mdm2 (mdm2)

MBS1120129-01mgEColi 0.1mg(E-Coli)
EUR 1210

Recombinant Xenopus laevis E3 ubiquitin-protein ligase Mdm2 (mdm2)

MBS1120129-01mgYeast 0.1mg(Yeast)
EUR 1290

Recombinant Mesocricetus auratus E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS1280919-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1335

Recombinant Mesocricetus auratus E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS1280919-002mgEColi 0.02mg(E-Coli)
EUR 1025

Recombinant Mesocricetus auratus E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS1280919-002mgYeast 0.02mg(Yeast)
EUR 1125

Recombinant Mesocricetus auratus E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS1280919-01mgEColi 0.1mg(E-Coli)
EUR 1195

Recombinant Mesocricetus auratus E3 ubiquitin-protein ligase Mdm2 (MDM2)

MBS1280919-01mgYeast 0.1mg(Yeast)
EUR 1285

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-1mg

QP6353-ec-1mg 1mg
EUR 2763.6

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-100ug

QP6353-ec-100ug 100ug
EUR 685.2

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-10ug

QP6353-ec-10ug 10ug
EUR 326.4

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-200ug

QP6353-ec-200ug 200ug
EUR 1077.6

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-500ug

QP6353-ec-500ug 500ug
EUR 1816.8

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, E.coli-50ug

QP6353-ec-50ug 50ug
EUR 434.4

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-10ug

QP6353-ye-10ug 10ug
EUR 326.4

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-1mg

QP6353-ye-1mg 1mg
EUR 2763.6

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-50ug

QP6353-ye-50ug 50ug
EUR 424.8

Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

EK9759 96Т
EUR 799

Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33932MO-48Tests 48 Tests
EUR 325
Description: Mouse (Mus musculus)

Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33932MO-96Tests 96 Tests
EUR 610
Description: Mouse (Mus musculus)

Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33932MO-48T 48T
EUR 325
Description: Mouse (Mus musculus)

Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33932MO-96T 96T
EUR 610
Description: Mouse (Mus musculus)

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-100ug

QP6353-ye-100ug 100ug
EUR 685.2

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-200ug

QP6353-ye-200ug 200ug
EUR 1077.6

Recombinant Mouse E3 ubiquitin-protein ligase Mdm2 Protein, His, Yeast-500ug

QP6353-ye-500ug 500ug
EUR 1806

Human E3 ubiquitin- protein ligase Mdm2, MDM2 ELISA KIT

ELI-48185h 96tests
EUR 696

Mouse Mdm2 / E3 ubiquitin-protein ligase Mdm2 ELISA Kit

E12872m 96T
EUR 776

Mouse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit

MBS2890079-10x96StripWells 10x96-Strip-Wells
EUR 4080

Mouse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit

MBS2890079-48StripWells 48-Strip-Wells
EUR 390

Mouse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit

MBS2890079-5x96StripWells 5x96-Strip-Wells
EUR 2220

Mouse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit

MBS2890079-96StripWells 96-Strip-Wells
EUR 520

Recombinant human E3 ubiquitin-protein ligase Mdm2

P1360 100ug Ask for price
Description: Recombinant protein for human E3 ubiquitin-protein ligase Mdm2

ELISA kit for Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2)

KTE71081-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2)

KTE71081-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2)

KTE71081-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Mouse E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody

abx344959-100l 100 µl
EUR 350

E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody

abx344959-50l 50 µl
EUR 250

E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (HRP)

abx344960-100g 100 µg Ask for price

E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (HRP)

abx344960-20g 20 µg
EUR 250

E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (HRP)

abx344960-50g 50 µg
EUR 350

E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (FITC)

abx344961-100g 100 µg Ask for price

E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (FITC)

abx344961-20g 20 µg
EUR 250

E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (FITC)

abx344961-50g 50 µg
EUR 350

E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (Biotin)

abx344962-100g 100 µg Ask for price

E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (Biotin)

abx344962-20g 20 µg
EUR 250

E3 ubiquitin-protein ligase Mdm2 (MDM2) Antibody (Biotin)

abx344962-50g 50 µg
EUR 350

Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

EK9763 96Т
EUR 799

Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33936CA-48Tests 48 Tests
EUR 360
Description: Cat (Felis catus,Feline)

Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33936CA-96Tests 96 Tests
EUR 680
Description: Cat (Felis catus,Feline)

Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33936CA-48T 48T
EUR 360
Description: Cat (Felis catus,Feline)

Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33936CA-96T 96T
EUR 680
Description: Cat (Felis catus,Feline)

Cat E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS9335234-INQUIRE INQUIRE Ask for price

Dog E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS9331780-10x96StripWells 10x96-Strip-Wells
EUR 6725

Dog E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS9331780-48StripWells 48-Strip-Wells
EUR 550

Dog E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS9331780-5x96StripWells 5x96-Strip-Wells
EUR 3420

Dog E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS9331780-96StripWells 96-Strip-Wells
EUR 765

Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

MBS285237-10x96StripWells 10x96-Strip-Wells
EUR 6840

Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

MBS285237-48StripWells 48-Strip-Wells
EUR 480

Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

MBS285237-5x96StripWells 5x96-Strip-Wells
EUR 3610

Cat E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

MBS285237-96StripWells 96-Strip-Wells
EUR 805

MDM2, CK1d, Active, Recombinant, Human, GST-Tag (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2)

MBS636694-001mg 0.01mg
EUR 1310

MDM2, CK1d, Active, Recombinant, Human, GST-Tag (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2)

MBS636694-5x001mg 5x0.01mg
EUR 5685

Human E3 ubiquitin-protein ligase Mdm2(MDM2) Elisa Kit

EK712991 96 Wells
EUR 0.31

Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

EK9760 96Т
EUR 799

Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

EK9761 96Т
EUR 799

Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33933HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33933HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33934HO-48Tests 48 Tests
EUR 360
Description: Horse (Equus caballus; Equine)

Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33934HO-96Tests 96 Tests
EUR 680
Description: Horse (Equus caballus; Equine)

Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA KIT

E5213Hu-1096T 10*96T
EUR 4122

Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA KIT

E5213Hu-48wells 48 wells
EUR 300

Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA KIT

E5213Hu-596T 5*96T
EUR 2061

Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA KIT

E5213Hu-96wells 96 wells
EUR 458

Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

KTE61676-48T 48T
EUR 339
Description: This Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit employs a two-site sandwich ELISA to quantitate MDM2.

Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

KTE61676-96T 96T
EUR 589
Description: This Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit employs a two-site sandwich ELISA to quantitate MDM2.

Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

KTE61676-96T5 96 T×5
EUR 2629
Description: This Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit employs a two-site sandwich ELISA to quantitate MDM2.

Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

KTE61676-96T50 96 T×50
EUR 24569
Description: This Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit employs a two-site sandwich ELISA to quantitate MDM2.

Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA kit

ELK8761-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Mdm2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Mdm2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human Mdm2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Mdm2 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA kit

ELK8761-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Mdm2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Mdm2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human Mdm2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Mdm2 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33933HU-48T 48T
EUR 325
Description: Human (Homo sapiens)

Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33933HU-96T 96T
EUR 610
Description: Human (Homo sapiens)

Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33934HO-48T 48T
EUR 360
Description: Horse (Equus caballus; Equine)

Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33934HO-96T 96T
EUR 680
Description: Horse (Equus caballus; Equine)

Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS8807685-10x96StripWells 10x96-Strip-Wells
EUR 3130

Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS8807685-48StripWells 48-Strip-Wells
EUR 350

Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS8807685-5x96StripWells 5x96-Strip-Wells
EUR 1710

Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS8807685-96StripWells 96-Strip-Wells
EUR 445

Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS1606129-10x96StripWells 10x96-Strip-Wells
EUR 3460

Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS1606129-48StripWells 48-Strip-Wells
EUR 285

Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS1606129-5x96StripWells 5x96-Strip-Wells
EUR 1750

Human E3 ubiquitin-protein ligase Mdm2, MDM2 ELISA Kit

MBS1606129-96StripWells 96-Strip-Wells
EUR 425

Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

MBS280775-10x96StripWells 10x96-Strip-Wells
EUR 6840

Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

MBS280775-48StripWells 48-Strip-Wells
EUR 480

Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

MBS280775-5x96StripWells 5x96-Strip-Wells
EUR 3610

Horse E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

MBS280775-96StripWells 96-Strip-Wells
EUR 805

Human E3 Ubiquitin-Protein Ligase Mdm2 (MDM2) ELISA Kit

MBS9715340-48Tests 48Tests
EUR 340

Human E3 Ubiquitin-Protein Ligase Mdm2 (MDM2) ELISA Kit

MBS9715340-5x96Tests 5x96Tests
EUR 1820

Human E3 Ubiquitin-Protein Ligase Mdm2 (MDM2) ELISA Kit

MBS9715340-96Tests 96Tests
EUR 500

Dog MDM2 / E3 ubiquitin-protein ligase Mdm2 ELISA Kit

E12872d 96T
EUR 900

Dog MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit

MBS2890075-10x96StripWells 10x96-Strip-Wells
EUR 4630

Dog MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit

MBS2890075-48StripWells 48-Strip-Wells
EUR 440

Dog MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit

MBS2890075-5x96StripWells 5x96-Strip-Wells
EUR 2480

Dog MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit

MBS2890075-96StripWells 96-Strip-Wells
EUR 580

Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

EK9762 96Т
EUR 799

Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33935DO-48Tests 48 Tests
EUR 360
Description: Canine (Canis familiaris; Dog)

Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33935DO-96Tests 96 Tests
EUR 680
Description: Canine (Canis familiaris; Dog)

Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33935DO-48T 48T
EUR 360
Description: Canine (Canis familiaris; Dog)

Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

AE33935DO-96T 96T
EUR 680
Description: Canine (Canis familiaris; Dog)

Mouse E3 ubiquitin-protein ligase Mdm2 ELISA kit

E01A23588 96T
EUR 700
Description: ELISA

Human MDM2 / E3 ubiquitin-protein ligase Mdm2 ELISA Kit

E12872h 96T
EUR 736

Human MDM2 (E3 ubiquitin-protein ligase Mdm2) ELISA Kit

MBS7615239-10x96StripWells 10x96-Strip-Wells
EUR 3900

Human MDM2 (E3 ubiquitin-protein ligase Mdm2) ELISA Kit

MBS7615239-48StripWells 48-Strip-Wells
EUR 340

Human MDM2 (E3 ubiquitin-protein ligase Mdm2) ELISA Kit

MBS7615239-5x96StripWells 5x96-Strip-Wells
EUR 2045

Human MDM2 (E3 ubiquitin-protein ligase Mdm2) ELISA Kit

MBS7615239-96StripWells 96-Strip-Wells
EUR 455

Horse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit

MBS2890078-10x96StripWells 10x96-Strip-Wells
EUR 4080

Horse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit

MBS2890078-48StripWells 48-Strip-Wells
EUR 390

Horse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit

MBS2890078-5x96StripWells 5x96-Strip-Wells
EUR 2220

Horse MDM2/E3 Ubiquitin-Protein Ligase Mdm2 ELISA Kit

MBS2890078-96StripWells 96-Strip-Wells
EUR 520

Human E3 ubiquitin-Protein Ligase Mdm2, MDM2 GENLISA ELISA

KBH5213 1 x 96 wells
EUR 286

MDM2, Active, Recombinant, Human, c-Myc GST-Tag (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2)

MBS638318-001mg 0.01mg
EUR 1310

MDM2, Active, Recombinant, Human, c-Myc GST-Tag (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2)

MBS638318-5x001mg 5x0.01mg
EUR 5685

MDM2 (untagged) - Human MDM2 proto-oncogene, E3 ubiquitin protein ligase (MDM2), transcript variant 5

SC335322 10 µg Ask for price

ELISA kit for Human E3 ubiquitin-protein ligase Mdm2 (MDM2)

KTE61676-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Human E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (AP)

MBS6132264-01mL 0.1(mL
EUR 875

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (AP)

MBS6132264-5x01mL 5x0.1mL
EUR 3800

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (PE)

MBS6158779-01mL 0.1(mL
EUR 875

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (PE)

MBS6158779-5x01mL 5x0.1mL
EUR 3800

ELISA kit for Canine E3 ubiquitin-protein ligase Mdm2 (MDM2)

KTE20069-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Canine E3 ubiquitin-protein ligase Mdm2 (MDM2)

KTE20069-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Canine E3 ubiquitin-protein ligase Mdm2 (MDM2)

KTE20069-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Canine E3 ubiquitin-protein ligase Mdm2 (MDM2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) APC

MBS6137567-01mL 0.1(mL
EUR 875

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) APC

MBS6137567-5x01mL 5x0.1mL
EUR 3800

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (Biotin)

MBS6142870-01mL 0.1(mL
EUR 875

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (Biotin)

MBS6142870-5x01mL 5x0.1mL
EUR 3800

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (FITC)

MBS6148173-01mL 0.1(mL
EUR 875

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (FITC)

MBS6148173-5x01mL 5x0.1mL
EUR 3800

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (HRP)

MBS6153476-01mL 0.1(mL
EUR 875

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (HRP)

MBS6153476-5x01mL 5x0.1mL
EUR 3800

Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (AP)

MBS6487469-02mL 0.2mL
EUR 980

Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (AP)

MBS6487469-5x02mL 5x0.2mL
EUR 4250

Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (PE)

MBS6487479-02mL 0.2mL
EUR 980

Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (PE)

MBS6487479-5x02mL 5x0.2mL
EUR 4250

MDM2 (myc-DDK-tagged) - Human MDM2 proto-oncogene, E3 ubiquitin protein ligase (MDM2), transcript variant 5

RC237428 10 µg Ask for price

MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (AP)

MBS6487458-02mL 0.2mL
EUR 980

MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (AP)

MBS6487458-5x02mL 5x0.2mL
EUR 4250

MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (APC)

MBS6487459-02mL 0.2mL
EUR 980

MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (APC)

MBS6487459-5x02mL 5x0.2mL
EUR 4250

MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (FITC)

MBS6487461-02mL 0.2mL
EUR 980

MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (FITC)

MBS6487461-5x02mL 5x0.2mL
EUR 4250

MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (PE)

MBS6487468-02mL 0.2mL
EUR 980

MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (PE)

MBS6487468-5x02mL 5x0.2mL
EUR 4250

Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (APC)

MBS6487470-02mL 0.2mL
EUR 980

Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (APC)

MBS6487470-5x02mL 5x0.2mL
EUR 4250

Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (Biotin)

MBS6487471-02mL 0.2mL
EUR 980

Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (Biotin)

MBS6487471-5x02mL 5x0.2mL
EUR 4250

Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (FITC)

MBS6487472-02mL 0.2mL
EUR 980

Mdm2, CT (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (FITC)

MBS6487472-5x02mL 5x0.2mL
EUR 4250

MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (Biotin)

MBS6487460-02mL 0.2mL
EUR 980

MDM2 (S166) (Ubiquitin-protein Ligase E3 Mdm2, p53-binding Protein Mdm2, Oncoprotein Mdm2, Double Minute 2 Protein, Hdm2) (Biotin)

MBS6487460-5x02mL 5x0.2mL
EUR 4250

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (MaxLight 490)

MBS6201802-01mL 0.1(mL
EUR 875

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (MaxLight 490)

MBS6201802-5x01mL 5x0.1mL
EUR 3800

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (MaxLight 550)

MBS6212477-01mL 0.1(mL
EUR 875

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (MaxLight 550)

MBS6212477-5x01mL 5x0.1mL
EUR 3800

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (MaxLight 405)

MBS6191127-01mL 0.1(mL
EUR 875

MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (MaxLight 405)

MBS6191127-5x01mL 5x0.1mL
EUR 3800
OED can be utilized to outline the set of experiments that might (a) establish the very best mannequin or (b) enhance the identifiability of unknown parameters. In this chapter, we current an in depth sensible process to compute optimum experiments utilizing the AMIGO2 toolbox.

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