Over the previous decade, we’ve got witnessed an growing quantity of large-scale research which have supplied multi-omics information by high-throughput sequencing approaches. This has notably helped with figuring out key (epi)genetic alterations in cancers. Importantly, aberrations that result in the activation of signaling networks by way of the disruption of regular mobile homeostasis is seen each in most cancers cells and additionally within the neighboring tumor microenvironment.
Cancer methods biology approaches have enabled the environment friendly integration of experimental information with computational algorithms and the implementation of actionable focused therapies, because the exceptions, for the remedy of most cancers. Comprehensive multi-omics information obtained by way of the sequencing of tumor samples and experimental mannequin methods will probably be necessary in implementing novel most cancers methods biology approaches and growing their efficacy for tailoring novel personalised remedy modalities in most cancers.
In this overview, we talk about rising most cancers methods biology approaches based mostly on multi-omics information derived from bulk and single-cell genomics research along with current experimental mannequin methods that play a essential position in understanding (epi)genetic heterogeneity and remedy resistance in most cancers.
The finest predictions in experimental biology are essential and persuasive
A robust option to consider scientific explanations (hypotheses) is to check the predictions that they make. In this fashion, predictions function an necessary bridge between summary hypotheses and concrete experiments. Experimental biologists, nonetheless, typically obtain little steerage on easy methods to generate high quality predictions. Here, we establish two necessary elements of good predictions – criticality and persuasiveness – which relate to the power of a prediction (and the experiment it implies) to disprove a speculation or to persuade a skeptic that the speculation has benefit.
Using an in depth instance, we reveal how striving for predictions which are each essential and persuasive can pace scientific progress by main us to extra highly effective experiments. Finally, we offer a top quality management guidelines to help college students and researchers as they navigate the hypothetico-deductive methodology from puzzling observations to experimental checks.
Literature-based studying and experimental design mannequin in molecular biology educating for medical college students at Tongji University
In 2018, to assist undergraduate medical college students strengthen their self-learning and scientific analysis expertise, we launched an tutorial mannequin that mixed literature-based studying with experimental design. We examined this mannequin on the molecular biology class at Tongji University. In step one of the mannequin, a subject is chosen, and college students discover, learn, and consider scientific papers in teams and ship shows.
In the second step, they design scientific experiments in teams and talk about their proposed experiments at school, which is to be adopted by additional experimental verification within the lab course. This total exercise was given 20% weightage within the ultimate rating. The mannequin led to raised student-centered educating and self-directed studying in line with quantitative and qualitative evaluation. Students confirmed nice curiosity in literature and analysis.
They loved group work and gained expertise in group and presentation. Apart from a major improve in ultimate rating, evaluation information from college students indicated that they have been glad with this educating mannequin and thought-about it a optimistic expertise. Looking on the optimistic affect of the literature-based studying and experiment design mannequin, we help its continued use for educating molecular biology to undergraduate medical college students.
Increased Scaffolding and Inquiry in an Introductory Biology Lab Enhance Experimental Design Skills and Sense of Scientific Ability
We current a mannequin for the method of redesigning the laboratory curriculum in Introductory Organismal Biology to extend alternatives for significant inquiry and improve pupil recognition of their scientific ability growth. We created scaffolded modules and assignments to permit college students to construct and follow key expertise in experimental design, information evaluation, and scientific writing.
Using the Tool for Interrelated Experimental Design, we confirmed considerably larger features in experimental design scores within the redesigned course and a extra constant sample of features throughout a variety of preliminary pupil scores in contrast with the unique format. Students who accomplished the redesigned course rated themselves considerably larger in experimental design, information assortment, and information evaluation expertise in contrast with college students within the authentic format.
Scores on the Laboratory Course Activity Survey have been excessive for each codecs and didn’t considerably differ. However, on written course evaluations, college students within the redesigned course have been extra prone to report that they engaged in “actual science” and their “personal experiments.” They additionally had elevated recognition of their particular analytical and writing ability growth. Our outcomes reveal that intentional, scaffolded instruction utilizing inquiry modules can improve experimental design expertise and sense of scientific potential in an introductory biology course.
The ITGB6 gene: its position in experimental and medical biology
Integrin αvβ6 is a membrane-spanning heterodimeric glycoprotein concerned in wound therapeutic and the pathogenesis of ailments together with fibrosis and most cancers. Therefore, it’s of nice medical curiosity for us to grasp the molecular mechanisms of its biology.
Rat Mucin 2 (MUC2) ELISA Kit |
DLR-MUC2-Ra-48T |
DL Develop |
48T |
EUR 609.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Mucin 2 (MUC2) in samples from tissue homogenates, cell lysates or other biological fluids. |
Rat Mucin 2 (MUC2) ELISA Kit |
DLR-MUC2-Ra-96T |
DL Develop |
96T |
EUR 793.2 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Mucin 2 (MUC2) in samples from tissue homogenates, cell lysates or other biological fluids. |
Mouse Mucin 2 (MUC2) ELISA Kit |
RD-MUC2-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 586.8 |
Mouse Mucin 2 (MUC2) ELISA Kit |
RD-MUC2-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 812.4 |
Rat Mucin 2 (MUC2) ELISA Kit |
RD-MUC2-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 613.2 |
Rat Mucin 2 (MUC2) ELISA Kit |
RD-MUC2-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 850.8 |
Mouse Mucin 2 (MUC2) ELISA Kit |
RDR-MUC2-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 613.2 |
Mouse Mucin 2 (MUC2) ELISA Kit |
RDR-MUC2-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 850.8 |
Rat Mucin 2 (MUC2) ELISA Kit |
RDR-MUC2-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 640.8 |
Rat Mucin 2 (MUC2) ELISA Kit |
RDR-MUC2-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 890.4 |
Human Mucin-2 (MUC2) |
1-CSB-EP015222HU |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Mucin-2(MUC2),partial expressed in E.coli |
Human Mucin-2 (MUC2) |
1-CSB-EP015222HUa0 |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Mucin-2(MUC2),partial expressed in E.coli |
Human Mucin-2 (MUC2) |
1-CSB-YP015222HU |
Cusabio |
-
EUR 516.00
-
EUR 280.80
-
EUR 1809.60
-
EUR 770.40
-
EUR 1210.80
-
EUR 349.20
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Mucin-2(MUC2),partial expressed in Yeast |
Human Mucin 2 (MUC2) Protein |
20-abx068092 |
Abbexa |
-
EUR 777.60
-
EUR 326.40
-
EUR 2331.60
-
EUR 910.80
-
EUR 560.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mucin 2 (MUC2) Antibody |
20-abx100188 |
Abbexa |
-
EUR 477.60
-
EUR 159.60
-
EUR 1328.40
-
EUR 644.40
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mucin 2 (MUC2) Antibody |
20-abx100190 |
Abbexa |
-
EUR 493.20
-
EUR 159.60
-
EUR 1362.00
-
EUR 661.20
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mucin 2 (MUC2) Antibody |
20-abx100191 |
Abbexa |
-
EUR 360.00
-
EUR 159.60
-
EUR 927.60
-
EUR 493.20
-
EUR 309.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mucin 2 (MUC2) Antibody |
20-abx100192 |
Abbexa |
-
EUR 493.20
-
EUR 159.60
-
EUR 1362.00
-
EUR 661.20
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mucin 2 (MUC2) Antibody |
20-abx173624 |
Abbexa |
|
|
|
Mucin 2 (MUC2) Antibody |
20-abx132407 |
Abbexa |
-
EUR 376.80
-
EUR 944.40
-
EUR 493.20
-
EUR 184.80
-
EUR 309.60
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Mucin 2 (MUC2) Antibody |
20-abx129925 |
Abbexa |
-
EUR 560.40
-
EUR 159.60
-
EUR 1629.60
-
EUR 777.60
-
EUR 427.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mucin-2 (MUC2) Antibody |
20-abx211009 |
Abbexa |
|
|
|
Mucin-2 (MUC2) Antibody |
20-abx211010 |
Abbexa |
|
|
|
Mucin-2 (MUC2) Antibody |
abx413310-02mg |
Abbexa |
0.2 mg |
EUR 678 |
|
Mucin-2 (MUC2) Antibody |
20-abx304587 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Mucin 2 (MUC2) Antibody |
20-abx177611 |
Abbexa |
|
|
|
Mucin 2 (MUC2) Antibody |
20-abx177612 |
Abbexa |
|
|
|
Mucin 2 (MUC2) Antibody |
20-abx177613 |
Abbexa |
-
EUR 543.60
-
EUR 159.60
-
EUR 1545.60
-
EUR 744.00
-
EUR 410.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mucin 2 (MUC2) Antibody |
abx216977-100ug |
Abbexa |
100 ug |
EUR 526.8 |
|
Native Mucin 2 (MUC2) |
4-NPA705Po01 |
Cloud-Clone |
-
EUR 571.58
-
EUR 276.00
-
EUR 1813.44
-
EUR 684.48
-
EUR 1248.96
-
EUR 458.40
-
EUR 4353.60
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Pig Mucin 2 expressed in: Pig |
Recombinant Mucin 2 (MUC2) |
4-RPA705Hu01 |
Cloud-Clone |
-
EUR 550.08
-
EUR 271.20
-
EUR 1732.80
-
EUR 657.60
-
EUR 1195.20
-
EUR 444.00
-
EUR 4152.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Mucin 2 expressed in: E.coli |
Recombinant Mucin 2 (MUC2) |
4-RPA705Mu01 |
Cloud-Clone |
-
EUR 567.29
-
EUR 274.80
-
EUR 1797.31
-
EUR 679.10
-
EUR 1238.21
-
EUR 454.80
-
EUR 4313.28
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Mucin 2 expressed in: E.coli |
Recombinant Mucin 2 (MUC2) |
4-RPA705Mu02 |
Cloud-Clone |
-
EUR 605.99
-
EUR 285.60
-
EUR 1942.46
-
EUR 727.49
-
EUR 1334.98
-
EUR 481.20
-
EUR 4676.16
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Mucin 2 expressed in: E.coli |
Recombinant Mucin 2 (MUC2) |
4-RPA705Mu03 |
Cloud-Clone |
-
EUR 567.29
-
EUR 274.80
-
EUR 1797.31
-
EUR 679.10
-
EUR 1238.21
-
EUR 454.80
-
EUR 4313.28
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Mucin 2 expressed in: E.coli |
MUC2 Antibody / Mucin 2 |
V7968-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V7968-20UG |
NSJ Bioreagents |
20 ug |
EUR 219 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V7968SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V2197-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: This antibody recognizes a single glycoprotein of 520kDa, identified as MUC2 (Mucin-2). The MUC2 antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine and colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V2197-20UG |
NSJ Bioreagents |
20 ug |
EUR 219 |
Description: This antibody recognizes a single glycoprotein of 520kDa, identified as MUC2 (Mucin-2). The MUC2 antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine and colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V2197IHC-7ML |
NSJ Bioreagents |
7 ml |
EUR 499 |
Description: This antibody recognizes a single glycoprotein of 520kDa, identified as MUC2 (Mucin-2). The MUC2 antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine and colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V2197SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: This antibody recognizes a single glycoprotein of 520kDa, identified as MUC2 (Mucin-2). The MUC2 antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine and colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V7125-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: Mucin 2 coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. [UniProt] |
MUC2 Antibody / Mucin 2 |
V7125-20UG |
NSJ Bioreagents |
20 ug |
EUR 219 |
Description: Mucin 2 coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. [UniProt] |
MUC2 Antibody / Mucin 2 |
V7125IHC-7ML |
NSJ Bioreagents |
7 ml |
EUR 499 |
Description: Mucin 2 coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. [UniProt] |
MUC2 Antibody / Mucin 2 |
V7125SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: Mucin 2 coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. [UniProt] |
MUC2 Antibody / Mucin 2 |
V7308-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V7308-20UG |
NSJ Bioreagents |
20 ug |
EUR 219 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V7308IHC-7ML |
NSJ Bioreagents |
7 ml |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V7308SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V2729-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V2729-20UG |
NSJ Bioreagents |
20 ug |
EUR 219 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V2729IHC-7ML |
NSJ Bioreagents |
7 ml |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V2729SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V9049-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V9049-20UG |
NSJ Bioreagents |
20 ug |
EUR 219 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V9049IHC-7ML |
NSJ Bioreagents |
7 ml |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V9049SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V9050-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V9050-20UG |
NSJ Bioreagents |
20 ug |
EUR 219 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V9050IHC-7ML |
NSJ Bioreagents |
7 ml |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
MUC2 Antibody / Mucin 2 |
V9050SAF-100UG |
NSJ Bioreagents |
100 ug |
EUR 499 |
Description: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. |
Human Mucin 2(MUC2) ELISA Kit |
CSB-E13122h-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Human Mucin 2 (MUC2) in samples from serum, plasma, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Human Mucin 2(MUC2) ELISA Kit |
1-CSB-E13122h |
Cusabio |
-
EUR 1080.00
-
EUR 6571.20
-
EUR 3480.00
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Human Mucin 2(MUC2) in samples from serum, plasma, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Human MUC2/ Mucin-2 ELISA Kit |
E1669Hu |
Sunlong |
1 Kit |
EUR 685.2 |
Human Mucin-2 (MUC2) ELISA Kit |
20-abx152395 |
Abbexa |
-
EUR 7970.40
-
EUR 4250.40
-
EUR 990.00
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Human Mucin-2 (MUC2) ELISA Kit |
abx055282-96tests |
Abbexa |
96 tests |
EUR 848.4 |
|
Human Mucin 2 (MUC2) CLIA Kit |
abx196012-96tests |
Abbexa |
96 tests |
EUR 990 |
|
Human Mucin-2 (MUC2) ELISA Kit |
20-abx572107 |
Abbexa |
-
EUR 7970.40
-
EUR 4250.40
-
EUR 990.00
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Human Mucin-2 (MUC2) CLIA Kit |
20-abx491916 |
Abbexa |
-
EUR 9567.60
-
EUR 5095.20
-
EUR 1177.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Human Mucin-2 (MUC2) ELISA Kit |
abx250256-96tests |
Abbexa |
96 tests |
EUR 848.4 |
|
Mucin 2 (MUC2) Monoclonal Antibody (Human) |
4-MAA705Hu22 |
Cloud-Clone |
-
EUR 289.20
-
EUR 2900.40
-
EUR 724.80
-
EUR 361.20
-
EUR 253.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Mucin 2 (MUC2) |
Human MUC2(Mucin-2) ELISA Kit |
EH1017 |
FN Test |
96T |
EUR 628.92 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Mucin 2 (MUC2) Polyclonal Antibody (Human) |
4-PAA705Hu01 |
Cloud-Clone |
-
EUR 278.40
-
EUR 2742.00
-
EUR 688.80
-
EUR 346.80
-
EUR 249.60
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Mucin 2 (MUC2) |
Human Mucin 2 (MUC2) ELISA Kit |
SEA705Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5128.02 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Mucin 2 (MUC2) in tissue homogenates, cell lysates and other biological fluids. |
Human Mucin 2 (MUC2) ELISA Kit |
SEA705Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 527.48 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Mucin 2 (MUC2) in tissue homogenates, cell lysates and other biological fluids. |
Human Mucin 2 (MUC2) ELISA Kit |
SEA705Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 702.12 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Mucin 2 (MUC2) in tissue homogenates, cell lysates and other biological fluids. |
Human Mucin 2 (MUC2) ELISA Kit |
SEA705Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2799.54 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Mucin 2 (MUC2) in tissue homogenates, cell lysates and other biological fluids. |
Human Mucin 2 (MUC2) ELISA Kit |
4-SEA705Hu |
Cloud-Clone |
-
EUR 5188.80
-
EUR 2739.60
-
EUR 703.20
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Mucin 2 (MUC2) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
Human Mucin 2 ELISA Kit (MUC2) |
RK01895 |
Abclonal |
96 Tests |
EUR 625.2 |
Mouse Mucin 2 (MUC2) Protein |
20-abx068093 |
Abbexa |
-
EUR 794.40
-
EUR 326.40
-
EUR 2431.20
-
EUR 944.40
-
EUR 577.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mouse Mucin 2 (MUC2) Protein |
20-abx068094 |
Abbexa |
-
EUR 844.80
-
EUR 343.20
-
EUR 2614.80
-
EUR 1011.60
-
EUR 610.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mouse Mucin 2 (MUC2) Protein |
20-abx068095 |
Abbexa |
-
EUR 794.40
-
EUR 326.40
-
EUR 2431.20
-
EUR 944.40
-
EUR 577.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Pig Mucin 2 (MUC2) Protein |
20-abx168616 |
Abbexa |
-
EUR 794.40
-
EUR 326.40
-
EUR 2448.00
-
EUR 944.40
-
EUR 577.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mucin 2 (MUC2) Antibody Pair |
20-abx370315 |
Abbexa |
|
- 10 × 96 tests
- 5 × 96 tests
|
|
Mucin 2 (MUC2) Antibody Pair |
20-abx370346 |
Abbexa |
|
- 10 × 96 tests
- 5 × 96 tests
|
|
Rat Mucin 2 (MUC2) Protein |
20-abx654406 |
Abbexa |
-
EUR 811.20
-
EUR 343.20
-
EUR 2498.40
-
EUR 961.20
-
EUR 577.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Pig Mucin 2 (MUC2) Protein |
20-abx654407 |
Abbexa |
-
EUR 861.60
-
EUR 343.20
-
EUR 2665.20
-
EUR 1028.40
-
EUR 610.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mucin-2 (MUC2) Antibody (FITC) |
abx413311-01mg |
Abbexa |
0.1 mg |
EUR 610.8 |
|
Mucin 2 (MUC2) Antibody (FITC) |
20-abx274208 |
Abbexa |
-
EUR 543.60
-
EUR 292.80
-
EUR 1579.20
-
EUR 760.80
-
EUR 410.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mucin-2 (MUC2) Antibody (HRP) |
20-abx304588 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Mucin-2 (MUC2) Antibody (FITC) |
20-abx304589 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Mucin-2 (MUC2) Antibody (Biotin) |
20-abx304590 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Mucin 2 (MUC2) Antibody (Biotin) |
20-abx271766 |
Abbexa |
-
EUR 510.00
-
EUR 276.00
-
EUR 1429.20
-
EUR 693.60
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mucin 2 (MUC2) Antibody (Biotin) |
20-abx272581 |
Abbexa |
-
EUR 510.00
-
EUR 276.00
-
EUR 1462.80
-
EUR 710.40
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
ELISA kit for Human MUC2 (Mucin 2) |
E-EL-H0632 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 640.8 |
|
Description: A sandwich ELISA kit for quantitative measurement of Human MUC2 (Mucin 2) in samples from Serum, Plasma, Cell supernatant |
CLIA kit for Human MUC2 (Mucin 2) |
E-CL-H0484 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 700.8 |
|
Description: A sandwich CLIA kit for quantitative measurement of Human MUC2 (Mucin 2) in samples from Serum, Plasma, Cell supernatant |
ELISA kit for Human MUC2 (Mucin 2) |
ELK2010 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Mucin 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
ELISA kit for Human Mucin 2 (MUC2) |
KTE61458-48T |
Abbkine |
48T |
EUR 424.8 |
|
Description: Quantitative sandwich ELISA for measuring Human Mucin 2 (MUC2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Mucin 2 (MUC2) |
KTE61458-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2702.4 |
|
Description: Quantitative sandwich ELISA for measuring Human Mucin 2 (MUC2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Mucin 2 (MUC2) |
KTE61458-96T |
Abbkine |
96T |
EUR 686.4 |
|
Description: Quantitative sandwich ELISA for measuring Human Mucin 2 (MUC2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
Mucin 2 (MUC2) Monoclonal Antibody (Human), APC |
4-MAA705Hu22-APC |
Cloud-Clone |
-
EUR 403.20
-
EUR 3778.80
-
EUR 1057.20
-
EUR 512.40
-
EUR 258.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Mucin 2 (MUC2). This antibody is labeled with APC. |
Mucin 2 (MUC2) Monoclonal Antibody (Human), Biotinylated |
4-MAA705Hu22-Biotin |
Cloud-Clone |
-
EUR 366.00
-
EUR 2840.40
-
EUR 844.80
-
EUR 445.20
-
EUR 259.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Mucin 2 (MUC2). This antibody is labeled with Biotin. |
Mucin 2 (MUC2) Monoclonal Antibody (Human), Cy3 |
4-MAA705Hu22-Cy3 |
Cloud-Clone |
-
EUR 488.40
-
EUR 4988.40
-
EUR 1359.60
-
EUR 633.60
-
EUR 295.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Mucin 2 (MUC2). This antibody is labeled with Cy3. |
Mucin 2 (MUC2) Monoclonal Antibody (Human), FITC |
4-MAA705Hu22-FITC |
Cloud-Clone |
-
EUR 346.80
-
EUR 3046.80
-
EUR 868.80
-
EUR 433.20
-
EUR 230.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Mucin 2 (MUC2). This antibody is labeled with FITC. |
Mucin 2 (MUC2) Monoclonal Antibody (Human), HRP |
4-MAA705Hu22-HRP |
Cloud-Clone |
-
EUR 369.60
-
EUR 3294.00
-
EUR 936.00
-
EUR 464.40
-
EUR 243.60
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Mucin 2 (MUC2). This antibody is labeled with HRP. |
As the limiting binding accomplice within the heterodimer, the β6 subunit controls αvβ6 expression and availability. Here we describe our understanding of the ITGB6 gene encoding the β6 subunit, together with its construction, transcriptional and post-transcriptional regulation, the organic results noticed in ITGB6 poor mice and medical circumstances of ITGB6 mutations.